The excitatory action of acetylcholine on hippocampal neurones of the guinea pig and rat maintained in vitro
References (70)
- et al.
Intracellular studies on the action ofl-glutamic acid on spinal neurones of the cat
Brain Research
(1972) - et al.
The cholinergic pharmacology of hippocampal pyramidal cells: a microintophoretic study
Neuropharmacology
(1976) - et al.
Excitation of mammalian central neurones by acidic amino acids
Brain Research
(1972) Characterization of drug iontophoresis with a fast micro assay technique
Biophys. J.
(1976)The effect of septal nuclei stimulation on the release of acetylcholine from the rabbit hippocampus
Brain Research
(1975)- et al.
Muscarinic and cGMP induced membrane potential changes: differences in electrogenic mechanisms
Brain Research
(1978) - et al.
The interpretation of current voltage relations recorded from a sperical cel with a single microelectrode
Biophys. J.
(1972) Electrical changes in the membrane in junctional transmission
Biochim. biophys. Acta (Amst.)
(1973)- et al.
Brain acetylcholine levels in rats with septal lesions
Life Sci.
(1971) The time course of cellular responses to iontophoretically applied drugs
J. theoret. Biol.
(1977)
Transient response in a dendritic neuron model for current injection at one branch
Biophys. J.
Effects of electrical stimulation on acetylcholine levels in central cholinergic nerve terminals
Brain Research
Characteristic of CA1 neurones recorded intracellularly in the hippocampal in vitro slice preparation
Brain Research
The transverse hippocampal slice: a well defined cortical structure maintained in vitro
Brain Research
Acetylcholine release from the cholinergic septo-hippocampal pathway
Life Sci.
Effects of acetylcholine and cyclic GMP on input resistance of cortical neurones in awake cats
Brain Research
The mechanism of inhibition of neuronal activity by opiates in the spinal cord of cat
Brain Research
Cat spinal motoneurones exhibit topographic sensitivity to glutamate and glycine
Brain Research
A cholinergic mechanism in the spinal cord of cats
Neuropharmacology
Actions of γ-aminobutyric acid on sympathetic ganglion cells
J. Physiol. (Lond.)
Receptive fields of cones in the retina of the turtle
J. Physiol. (Lond.)
Micro-electrophoretic studies of neurones in the cat hippocampus
J. Physiol. (Lond.)
On the time course of the electrical response of salivary gland cells ofNauphoeta cinerea to iontophoretically applied dopamine
J. Physiol. (Lond.)
Rate of offset of action of slow-acting muscarinic antagonists is fast
Nature (Lond.)
On the latency and form of the membrane response of smooth muscle to the ioontophoretic application of acetylcholine or carbachol
Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone
Nature (Lond.)
Depolarization of neurones in the isolated olfactory cortex of the guinea pig by γ-aminobutyric acid
Brit. J. Pharmacol.
A stereotaxic animal frame with stepping motor-driven micromanipulator
J. Physiol. (Lond.)
Intracellular recording from pyramidal neurones in the in vitro transverse hippocampal slice
J. Physiol. (Lond.)
ACh-evoked excitation of cortical neurones
J. Physiol. (Lond.)
Intracellular recording from CA3 pyramidal neurones of hippocampal slices and the action of iontophoretic acetylcholine
Cortical inhibition and γ-aminobutyric acid
Exp. Brain Res.
Glutamic acid sensitivity of hippocampal pyramidal cell dendrites
Acta physiol. scand.
dl-Homocysteate-induced motoneurone depolarization with membrane conductance decrease
Brit. J. Pharmacol.
The action of N-methyl-d-aspartic and kainic acids on motoneurones with emphasis on conductance changes
Brit. J. Pharmacol.
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Modeling and simulation of organophosphate-induced neurotoxicity: Prediction and validation by experimental studies
2016, NeuroToxicologyCitation Excerpt :A major difference between glutamatergic and GABAergic synapses is that glutamatergic synapses are located on dendritic spines, whereas GABAergic synapses are located directly on dendritic shafts of pyramidal neurons. A number of pharmacological studies showed that ACh facilitates CA1 pyramidal cell discharges by blocking two distinct families of potassium channels, calcium-dependent potassium channels (SK, MK and BK) and the potassium channel responsible for the M current (KCNQ) that is functionally associated with the muscarinic ACh receptor type M1 (Biscoe and Straughan 1966; Benardo and Prince 1981; Dodd et al., 1981; Benardo et al., 1982; Halliwell and Adams, 1982; Krnjevic and Ropert 1982; Ropert and Krnjevic, 1982; Benardo and Prince, 1982a,b; Cole and Nicoll, 1983, 1984a,b; Muller and Misgeld, 1986). Calcium-dependent potassium channels are activated by increased intracellular calcium concentrations resulting from AP discharge and are responsible for the after-hyperpolarization (AHP) that follows AP production (Hotson and Prince, 1980; Alger and Nicoll, 1980a,b).
Acetylcholine, GABA and neuronal networks: A working hypothesis for compensations in the dystrophic brain
2015, Brain Research BulletinCitation Excerpt :It was shown that trains of stimuli delivered at 10–20 Hz, within the range at which putative septal cholinergic cells discharge during theta rhythm (Brazhnik and Fox, 1999), result in a robust recruitment of a mAChR-mediated synaptic response in interneurons and pyramidal neurons (Morton and Davies, 1997). mAChRs mediate excitement of pyramidal neurons by modulating ionic conductance directly and indirectly (Dodd et al., 1981; Cole and Nicoll, 1983; Halliwell, 1990). Activation of mAChRs was shown to have a double effect on GABAergic interneurons, directly increasing the frequency and amplitude of spontaneous inhibitory postsynaptic currents (IPSCs) while at the same time depressing monosynaptically evoked IPSCs and the frequency of mIPSCs (Behrends and ten Bruggencate, 1993).
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2003, Journal of Neuroscience MethodsStructural basis of the cholinergic and serotonergic modulation of GABAergic neurons in the hippocampus
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1998, Progress in Neurobiology
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Present address: Dept. of Neurobiology, Harvard Medical School, 25 Shattuck Street, Boston, Mass. 02115, U.S.A.
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Present address: Department of Pharmacology, The University of North Carolina at Chapel Hill, North Carolina, N.C. 27514, U.S.A.