Production of urine free dopamine from DOPA; A micropuncture study
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Neurons expressing individual enzymes of dopamine synthesis in the mediobasal hypothalamus of adult rats: Functional significance and topographic interrelations
2014, NeuroscienceCitation Excerpt :Hypothetically, l-DOPA can be involved in the regulation of target neurons in the brain and peripheral target cells including pituitary glandular cells via adrenoreceptors (Misu et al., 1996, 2003). Moreover, brain-derived l-DOPA may be involved in cooperative synthesis of catecholamines if captured from the general circulation into the peripheral monoenzymatic AADC-expressing cells, e.g. the epithelial cells of the kidney (Baines and Chan, 1980; Grossman et al., 1990). DA synthesized in peripheral monoenzymatic AADC-expressing cells, most probably, contributes to the autocrine or paracrine regulation, as it occurs in the kidney (Baines et al., 1992; Goldstein et al., 1995).
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