Elsevier

Virology

Volume 54, Issue 2, August 1973, Pages 536-539
Virology

Transformation of rat cells by DNA of human adenovirus 5

https://doi.org/10.1016/0042-6822(73)90163-3Get rights and content

Abstract

Primary rat embryo and baby rat kidney cells have been transformed by human adenovirus 5 DNA. Transforming activity was resistant to heating (1 hr at 56 °C), and to pronase, but was sensitive to DNase. The efficiency of transformation was approximately 1 transformed focus/μg DNA.

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