Research paperAnalysis of structural requirements for ah receptor antagonist activity: Ellipticines, flavones, and related compounds☆
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Keywords
ellipticines
flavones
Ah receptor binding
antagonism
Abbreviations
ANF, alpha-naphthoflavone
AhR, Ah receptor
ARNT, Ah receptor nuclear translocator, bHLH, basic helix-loop-helix
CYP1A1, cytochrome P4501A1
DRE, dioxin-responsive element
EMSA
electrophoretic mobility shift assay
and TCDD, 2,3,7,8-tetra-chlorodibenzo-p-dioxin
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This work was supported by NIH Grant ES02515, Center Grant ES01247, and Training Grant ES07026.
Copyright © 1996 Published by Elsevier Inc.