CommentaryKainate receptors in hippocampal CA3 subregion: evidence for a role in regulating neurotransmitter release
References (63)
- et al.
Brief seizure episodes induce long-term potentiation and mossy fibre sprouting in the hippocampus
Trends Neurosci.
(1990) - et al.
Cloning of a novel glutamate receptor subunit, Glu R5, expression in the nervous system during development
Neuron
(1990) - et al.
Cloning of a putative glutamate receptor, a low affinity kainate-binding subunit
Neuron
(1992) - et al.
Neurotransmitter receptors II—AMPA and kainate receptors
Neuropharmacol.
(1995) - et al.
Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit
Neuron
(1992) - et al.
Inhibition of [3H]γ-aminobutyric acid release by kainate receptor activation in rat hippocampal synaptosomes
Europ. J. Pharmacol.
(1997) - et al.
Effects of neonatal γ-ray irradiation on rat hippocampus—II. Development of excitatory amino acid binding sites
Neuroscience
(1991) - et al.
Presynaptic modulation of glutamate and dynorphin release by excitatory amino acids in the guinea-pig hippocampus
Neuroscience
(1991) - et al.
Regional distribution of transient [3H]kainic acid-binding sites in the central nervous system of the developing mouse, an autoradiographic study
Neurosci. Lett.
(1993) - et al.
The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits
Neuron
(1992)
A novel non-NMDA receptor antagonist shows selective displacement of low-affinity [3H]kainate binding
Europ. J. Pharmacol. -Mol. Pharmacol. Sec.
Determinants of Ca2+ permeability in both TM1 and TM2 of high affinity kainate receptor channels, diversity by RNA editing
Neuron
Glutamate receptors of the kainate type and synaptic transmission
Trends Neurosci.
High-affinity kainate and domoate receptors in rat brain
FEBS Lett.
A functionally active presynaptic high-affinity kainate receptor in the rat hippocampal CA3 subregion
Neurosci. Lett.
The ontogeny of excitatory amino acid receptors in the rat forebrain—II. Kainic acid receptors
Neuroscience
Structure and function of the NMDA receptor channel
Neuropharmacol.
Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells
Nature
Kainate binding sites in the hippocampal mossy fibers, localization and plasticity
Neuroscience
Synaptic expression of the high-affinity kainate receptor subunit KA2 in hippocampal cultures
Neuroscience
Excitatory amino acid action on the release of brain neurotransmitters and neuromodulators, biochemical studies
Prog. Neurobiol.
Metabotropic glutamate receptors in brain function and pathology
Trends Pharmacol. Sci.
Dendritic glutamate receptor channels in rat hippocampal CA3 and CA1 pyramidal neurons
J. Physiol.
Autoradiographic localization of high-affinity [3H]kainic acid binding sites in the rat forebrain
Europ. J. Pharmacol.
Structural determinants of ion flow through recombinant glutamate receptor channels
Science
Presynaptic plasticity, the regulation of Ca2+-dependent transmitter release
Prog. Neurobiol.
Cloning of a putative high-affinity kainate receptor expressed predominantly in hippocampal CA3 cells
Nature
A complex mosaic of high-affinity kainate receptors in rat brain
J. Neurosci.
Kainate receptor gene expression in the developing rat brain
J. Neurosci.
A map of non-NMDA receptor subunit expression in the vertebrate brain derived from in situ hybridization histochemistry
Long-lasting modification of the synaptic properties of rat CA3 hippocampal neurones induced by kainic acid
J. Physiol.
Cited by (50)
Life and death in the hippocampus: What's bad?
2021, Epilepsy and BehaviorCitation Excerpt :This sensitivity to degeneration may be associated with expression of KA receptors. Some authors have reported that KA receptors are highly expressed in the hippocampus and cause increased affinity of KA1 receptors, strongly expressed in CA3 cells, and weakly in CA1 [117–119], whereas KA2 receptors are highly expressed in both pyramidal cells [120,121]. The increased expression of these receptors may justify the susceptibility of CA3 region to the KA-induced excitotoxicity [122–124].
Interneurons secrete prosaposin, a neurotrophic factor, to attenuate kainic acid-induced neurotoxicity
2017, IBRO ReportsCitation Excerpt :These studies indicate PS plays an important role in the healing process of the injured nervous system. In the present study, the higher increase of PS in CA3 compared with CA1 is most likely because the concentration of KA receptors is highest in CA3 (Malva et al., 1998; Wang et al., 2005). Several alternatively spliced mRNAs are found for PS gene (Hiraiwa et al., 2003).
Deletion of Atf6α enhances kainate-induced neuronal death in mice
2016, Neurochemistry InternationalDecreased kainate receptors in the hippocampus of apolipoprotein D knockout mice
2010, Progress in Neuro-Psychopharmacology and Biological PsychiatryNeuroprotective potential of mGluR5 antagonist MTEP: Effects on kainate-induced excitotoxicity in the rat hippocampus
2010, Pharmacological ReportsCitation Excerpt :The aim of the present study was also to elucidate the mechanism responsible for the neuroprotective effect of MTEP. It is commonly known that KA excito-toxicity occurs mainly by excessive glutamate release [23, 24, 37]. Therefore, we tried to investigate possible influence of MTEP on KA-induced glutamate release in rat hippocampus using a microdialysis method.