Differential regulation of the cloned kappa and mu opioid receptors
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Keywords
potassium current
adenylyl cyclase
heterologous desensitization
homologous desensitization
somatostatin receptor
AtT-20 cells
Abbreviations
DAMGO, [D-Ala2,N-MePhe4,Gly-ol5]enkephalin
EGTA, ethyleneglycolbis(aminoethylether)tetra-acetate
GMP-PNP, guanylyl imidodiphosphate
HEPES, N-2-hydroxyethylpiperazine-N′-2-ethanesulphonic acid
IBMX, isobutylmethylxanthine
MK 678, c[N-Me-Ala-Tyr-D-Trp-Lys-Val-Phe]
nor-BNI, norbinaltorphimine
PTX, pertussis toxin
SRIF, somatostatin
U-50488, trans-(±)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]-benzeneacetamide methanesulfonate
U-69593, (+)-(5α7α,7β)-N-methyl-N-[7-(1-pyrrolidinyl)-1-oxaspiro[4,5]dec-8-yl]benzeneacetamide
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Copyright © 1998 IBRO. Published by Elsevier Ltd. All rights reserved.