Regulation of aquaporin-2 water channel trafficking by vasopressin
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The role of vasopressin and the vasopressin type V1a receptor agonist selepressin in septic shock
2017, Journal of Critical CareCitation Excerpt :Another important role of AVP is water homeostasis. V2 receptor activation leads to water channel aquaphorin 2 expression and translocation in the principal cells of the collecting tubule in the kidney [34,35]. The V2 receptor has also been shown to mediate vasodilation through NO [36,37].
Aquaporin expression and localization in the rabbit eye
2016, Experimental Eye ResearchCitation Excerpt :The mRNA expression results obtained by RT-PCR reflect that AQP1 is generally an ubiquitously expressed water channel. AQP2 is modulated by vasopressin (Knepper and Inoue, 1997) and regulates water- and electrolyte balance via the renal collecting ducts (Nielsen et al., 1993a). AQP2 mRNA analysis in ocular tissues did not show the presence of AQP2, although the primers amplified AQP2 mRNA using rabbit kidney total RNA as positive control.
NKCC1 and NKCC2: The pathogenetic role of cation-chloride cotransporters in hypertension
2015, Genes and DiseasesCitation Excerpt :As a consequence of this negative feedback loop, salt delivery to the distal nephron is kept within a narrow range. This process facilitates the fine adjustment of salt handling in the distal tubules by corticosteroids and peptide hormones, such as aldosterone and arginine vasopressin (AVP).42,43 Similar to TAHL, the apical membrane of the MD cells is abundant in NKCC2, which provides up to 80% of apical NaCl entry in these cells.44–46
Phosphatases Decrease Water and Urea Permeability in Rat Inner Medullary Collecting Ducts
2023, International Journal of Molecular Sciences