Elsevier

Life Sciences

Volume 74, Issue 17, 12 March 2004, Pages 2157-2184
Life Sciences

Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer

https://doi.org/10.1016/j.lfs.2003.09.047Get rights and content

Abstract

Cancer prevention and treatment using traditional Chinese medicines have attracted increasing interest. This study characterizes antioxidant activity and phenolic compounds of traditional Chinese medicinal plants associated with anticancer, comprising 112 species from 50 plant families. The improved ABTS•+ method was used to systematically assess the total antioxidant capacity (Trolox equivalent antioxidant capacity, TEAC) of the medicinal extracts. The TEAC values and total phenolic content for methanolic extracts of herbs ranged from 46.7 to 17,323 μmol Trolox equivalent/100 g dry weight (DW), and from 0.22 to 50.3 g of gallic acid equivalent/100 g DW, respectively. A positive, significant linear relationship between antioxidant activity and total phenolic content (all R2 values≥0.95) showed that phenolic compounds were the dominant antioxidant components in the tested medicinal herbs. Major types of phenolic compounds from most of the tested herbs were preliminarily identified and analyzed, and mainly included phenolic acids, flavonoids, tannins, coumarins, lignans, quinones, stilbenes, and curcuminoids. These medicinal herbs exhibited far stronger antioxidant activity and contained significantly higher levels of phenolics than common vegetables and fruits. Traditional Chinese medicinal plants associated with anticancer might be potential sources of potent natural antioxidants and beneficial chemopreventive agents.

Keywords

Antioxidant activity
Phenolic compounds
Anticancer
Traditional Chinese Medicines
ABTS
Phenolic acids
Flavonoids
Tannins
Quinones
Free radical

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