Abstract
THE duration of the bronchodilator action of isoprenaline (I, R1 = R2 = OH, R3 = Pri) is limited by metabolism by catechol-0-methyl transferase (COMT) to the inactive ether (I, R1 =OH, R2 = OMe, R3 = Pri) (ref. 1).
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References
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HARTLEY, D., JACK, D., LUNTS, L. et al. New Class of Selective Stimulants of β-Adrenergic Receptors. Nature 219, 861–862 (1968). https://doi.org/10.1038/219861a0
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DOI: https://doi.org/10.1038/219861a0
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