Abstract
Allosteric modulators allow for the fine-tuning of receptor responses to endogenous neurotransmitters and exogenous therapeutic agents. Different types of allosteric modulation of dopamine receptors are discussed as well as the significance of such modulation in the control of normal biological processes and in the treatment of disease.
Keywords: conformational change, regulation, modulate, plateau, catecholamine, biogenic amine, g protein-coupled receptor (gpcr), metal
Mini-Reviews in Medicinal Chemistry
Title: Allosteric Modulation of Dopamine Receptors
Volume: 5 Issue: 6
Author(s): John A. Schetz
Affiliation:
Keywords: conformational change, regulation, modulate, plateau, catecholamine, biogenic amine, g protein-coupled receptor (gpcr), metal
Abstract: Allosteric modulators allow for the fine-tuning of receptor responses to endogenous neurotransmitters and exogenous therapeutic agents. Different types of allosteric modulation of dopamine receptors are discussed as well as the significance of such modulation in the control of normal biological processes and in the treatment of disease.
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Cite this article as:
Schetz A. John, Allosteric Modulation of Dopamine Receptors, Mini-Reviews in Medicinal Chemistry 2005; 5 (6) . https://dx.doi.org/10.2174/1389557054023260
DOI https://dx.doi.org/10.2174/1389557054023260 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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