Interactions of n-tetraalkylammonium compounds and biguanides with a human renal organic cation transporter (hOCT2)

Pharm Res. 2002 Aug;19(8):1244-7. doi: 10.1023/a:1019870831174.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Biguanides / chemistry
  • Biguanides / pharmacokinetics*
  • Female
  • Humans
  • Organic Cation Transport Proteins / metabolism*
  • Organic Cation Transporter 2
  • Quaternary Ammonium Compounds / chemistry
  • Quaternary Ammonium Compounds / pharmacokinetics*
  • Xenopus laevis

Substances

  • Biguanides
  • Organic Cation Transport Proteins
  • Organic Cation Transporter 2
  • Quaternary Ammonium Compounds
  • SLC22A2 protein, human