Evaluation of enzyme inhibitors in drug discovery. A guide for medicinal chemists and pharmacologists

MeSH terms

• Chemistry, Pharmaceutical
• Combinatorial Chemistry Techniques
• Drug Design*
• Drug Evaluation, Preclinical
• Enzyme Inhibitors* / chemistry
• Enzyme Inhibitors* / metabolism
• Enzymes* / chemistry
• Enzymes* / genetics
• Enzymes* / metabolism
• Humans
• Models, Molecular
• Molecular Structure
• Protein Binding
• Protein Conformation
• Structure-Activity Relationship
• Substrate Specificity
• Technology, Pharmaceutical