New principle in QSAR: membrane requirements

J Recept Res. 1991;11(1-4):45-57. doi: 10.3109/10799899109066388.

Abstract

In this review I discuss our recent work on the possible role of the lipid phase of the target cell membrane in mediating receptor subtype selectivity of peptides.

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Catalysis
  • Membrane Lipids / physiology*
  • Molecular Sequence Data
  • Peptides / metabolism*
  • Receptors, Cell Surface / metabolism*
  • Structure-Activity Relationship

Substances

  • Membrane Lipids
  • Peptides
  • Receptors, Cell Surface