A dedicated Wnt secretion factor

Cell. 2006 May 5;125(3):432-3. doi: 10.1016/j.cell.2006.04.018.

Abstract

The Wnt family of signaling proteins mediates cell-cell communication during development. In this issue of Cell, Bänziger et al. (2006) and Bartscherer et al. (2006) identify Wntless/Evi, a multipass transmembrane protein in the secretory pathway of Wnt-producing cells that promotes Wnt secretion.

Publication types

  • Review
  • Comment

MeSH terms

  • Animals
  • Cell Communication / physiology
  • Cell Differentiation / physiology
  • Drosophila Proteins / genetics
  • Drosophila Proteins / isolation & purification
  • Drosophila Proteins / metabolism*
  • Drosophila melanogaster / embryology
  • Drosophila melanogaster / genetics
  • Drosophila melanogaster / metabolism*
  • Exocytosis / physiology
  • Membrane Proteins / genetics
  • Membrane Proteins / isolation & purification
  • Membrane Proteins / metabolism*
  • Protein Structure, Tertiary / physiology
  • Protein Transport / physiology
  • Signal Transduction / physiology
  • Wnt Proteins / genetics
  • Wnt Proteins / metabolism*

Substances

  • Drosophila Proteins
  • Membrane Proteins
  • Wnt Proteins