Abstract
Sheep naturally allergic to Ascaris suum antigen have been used to study the pathophysiology of asthma and more recently allergic rhinitis, chronic obstructive pulmonary disease (COPD) and cystic fibrosis. The utility of the model as it relates to the study of these diseases is discussed.
MeSH terms
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Animals
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Asthma / drug therapy
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Asthma / pathology
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Asthma / veterinary*
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Cystic Fibrosis / drug therapy
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Cystic Fibrosis / pathology
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Cystic Fibrosis / veterinary*
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Disease Models, Animal*
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Humans
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Pulmonary Disease, Chronic Obstructive / drug therapy
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Pulmonary Disease, Chronic Obstructive / pathology
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Pulmonary Disease, Chronic Obstructive / veterinary*
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Sheep
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Sheep Diseases / drug therapy*