No abstract available
Keywords:
FLT3 internal tandem duplications; FMS-like tyrosine kinase-3; acute myeloid leukaemia; ponatinib; tyrosine kinase inhibitor.
Publication types
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Clinical Trial, Phase I
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Letter
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Female
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Humans
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Imidazoles / therapeutic use*
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Leukemia, Myeloid, Acute / blood
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Leukemia, Myeloid, Acute / drug therapy*
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Leukemia, Myeloid, Acute / genetics
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Male
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Middle Aged
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Neoplasm Proteins / antagonists & inhibitors*
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Neoplasm Proteins / genetics
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Protein Kinase Inhibitors / therapeutic use*
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Pyridazines / therapeutic use*
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Recurrence
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Remission Induction
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Salvage Therapy
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Tandem Repeat Sequences
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fms-Like Tyrosine Kinase 3 / antagonists & inhibitors*
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fms-Like Tyrosine Kinase 3 / genetics
Substances
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Imidazoles
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Neoplasm Proteins
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Protein Kinase Inhibitors
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Pyridazines
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ponatinib
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FLT3 protein, human
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fms-Like Tyrosine Kinase 3