Functional selectivity at GPCRs: new opportunities in psychiatric drug discovery

Neuropsychopharmacology. 2014 Jan;39(1):248-9. doi: 10.1038/npp.2013.205.

Authors

Steven D Chang¹, Michael R Bruchas

Affiliation

¹ 1] Department of Anesthesiology, Washington University, St Louis, MO, USA [2] Department of Neurobiology, Washington University, St Louis, MO, USA [3] Department of Psychiatry, Washington University, St Louis, MO, USA.

No abstract available

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Drug Discovery*
Humans
Ligands
Mental Disorders / drug therapy*
Mental Disorders / metabolism
Protein Conformation / drug effects
Receptors, G-Protein-Coupled / metabolism*

Substances

Ligands
Receptors, G-Protein-Coupled

Grants and funding