Roles of G protein subunits in transmembrane signalling

E J Neer; D E Clapham

doi:10.1038/333129a0

Roles of G protein subunits in transmembrane signalling

Nature. 1988 May 12;333(6169):129-34. doi: 10.1038/333129a0.

Authors

E J Neer¹, D E Clapham

Affiliation

¹ Department of Medicine, Brigham and Women's Hospital Harvard Medical School, Boston, Massachusetts 02115.

PMID: 3130578
DOI: 10.1038/333129a0

Abstract

A family of proteins called G proteins couples cell surface receptors to a variety of enzymes and ion channels. Since many cells contain several very similar G proteins, an important question is how signals remain specific as they cross the cell membrane.

Publication types

Research Support, U.S. Gov't, P.H.S.
Review

MeSH terms

Animals
Cell Communication*
Cell Membrane / physiology*
GTP-Binding Proteins / physiology*

Substances

GTP-Binding Proteins