A novel mechanism for the inhibition of DNA synthesis following methylation: the effect of N-methyl-N-nitrosourea on HeLa cells

Chem Biol Interact. 1971 Oct;3(5):337-42. doi: 10.1016/0009-2797(71)90013-5.
No abstract available

MeSH terms

  • Alkylation
  • Animals
  • Cell Division / drug effects
  • Cricetinae
  • DNA / biosynthesis*
  • DNA Repair / drug effects
  • DNA Replication / drug effects
  • HeLa Cells / drug effects*
  • Kinetics
  • Methylation
  • Models, Biological
  • Nitroso Compounds / administration & dosage
  • Nitroso Compounds / pharmacology*
  • Nitrosourea Compounds
  • Protein Biosynthesis
  • Time Factors
  • Tritium
  • Urea / administration & dosage
  • Urea / pharmacology*

Substances

  • Nitroso Compounds
  • Nitrosourea Compounds
  • Tritium
  • Urea
  • DNA