Benserazide and carbidopa as substrates of catechol-O-methyltransferase: new mechanism of action in Parkinson's disease

Biochem Pharmacol. 1980 Dec 1;29(23):3123-6. doi: 10.1016/0006-2952(80)90574-2.
No abstract available

MeSH terms

  • 3,4-Dihydroxyphenylacetic Acid / metabolism
  • Animals
  • Benserazide / metabolism*
  • Benzyl Compounds / metabolism
  • Carbidopa / metabolism*
  • Catechol O-Methyltransferase / metabolism*
  • Hydrazines / metabolism*
  • Kinetics
  • Liver / enzymology*
  • Parkinson Disease / enzymology*
  • S-Adenosylmethionine / metabolism
  • Substrate Specificity
  • Swine

Substances

  • Benzyl Compounds
  • Hydrazines
  • 3,4-Dihydroxyphenylacetic Acid
  • 2,3,4-trihydroxybenzylhydrazine
  • Benserazide
  • S-Adenosylmethionine
  • Catechol O-Methyltransferase
  • Carbidopa