Review: molecular biology of transgenic animals

J Anim Sci. 1993:71 Suppl 3:1-9. doi: 10.2527/1993.71suppl_31x.

Abstract

The amazing pace of discovery within the field of molecular biology has expanded the understanding of as well as the potential for genetic engineering in laboratory and domestic animals. Recently, specific techniques have been perfected, including recombinant DNA, genetic cloning, analysis of gene expression, and the sequencing of nucleic acids and proteins. These molecular techniques combined with methods allowing transfer of the recombinant genes into living cells and fertilized eggs advent the production of transgenic mice and other animals, the application of which is unlimited.

Publication types

  • Review

MeSH terms

  • Animals
  • Animals, Genetically Modified / genetics*
  • Cloning, Molecular
  • DNA, Recombinant
  • Gene Expression
  • Molecular Biology / methods*
  • Sequence Analysis
  • Transfection

Substances

  • DNA, Recombinant