Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes
J Med Chem
.
1998 Mar 26;41(7):1007-10.
doi: 10.1021/jm970530e.
Authors
M Kansy
1
,
F Senner
,
K Gubernator
Affiliation
1
F. Hoffmann-La Roche Ltd., Basel, Switzerland.
PMID:
9544199
DOI:
10.1021/jm970530e
No abstract available
MeSH terms
Absorption
Adsorption
Caco-2 Cells
Drug Evaluation, Preclinical / methods*
Humans
Hydrogen-Ion Concentration
Intestinal Absorption
Membranes, Artificial*
Permeability
Pharmacokinetics*
Spectrophotometry, Ultraviolet
Substances
Membranes, Artificial