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Page 1
Genetically programmable pathogen sense and destroy.
ACS Synth Biol. 2013 Dec 20;2(12):715-23. doi: 10.1021/sb4000417. Epub 2013 Jul 2.
ACS Synth Biol. 2013.
PMID: 23763381
PCFT/SLC46A1 promoter methylation and restoration of gene expression in human leukemia cells.
Gonen N, Bram EE, Assaraf YG.
Gonen N, et al. Among authors: bram ee.
Biochem Biophys Res Commun. 2008 Nov 28;376(4):787-92. doi: 10.1016/j.bbrc.2008.09.074. Epub 2008 Sep 24.
Biochem Biophys Res Commun. 2008.
PMID: 18817749
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Imidazoacridinone-dependent lysosomal photodestruction: a pharmacological Trojan horse approach to eradicate multidrug-resistant cancers.
Adar Y, Stark M, Bram EE, Nowak-Sliwinska P, van den Bergh H, Szewczyk G, Sarna T, Skladanowski A, Griffioen AW, Assaraf YG.
Adar Y, et al. Among authors: bram ee.
Cell Death Dis. 2012 Apr 5;3(4):e293. doi: 10.1038/cddis.2012.30.
Cell Death Dis. 2012.
PMID: 22476101
Free PMC article.
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Heterogeneous nuclear ribonucleoprotein H1/H2-dependent unsplicing of thymidine phosphorylase results in anticancer drug resistance.
Stark M, Bram EE, Akerman M, Mandel-Gutfreund Y, Assaraf YG.
Stark M, et al. Among authors: bram ee.
J Biol Chem. 2011 Feb 4;286(5):3741-54. doi: 10.1074/jbc.M110.163444. Epub 2010 Nov 10.
J Biol Chem. 2011.
PMID: 21068389
Free PMC article.
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Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistance.
Bram EE, Stark M, Raz S, Assaraf YG.
Bram EE, et al.
Neoplasia. 2009 Dec;11(12):1359-70. doi: 10.1593/neo.91314.
Neoplasia. 2009.
PMID: 20019844
Free PMC article.
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C421 allele-specific ABCG2 gene amplification confers resistance to the antitumor triazoloacridone C-1305 in human lung cancer cells.
Bram EE, Ifergan I, Grimberg M, Lemke K, Skladanowski A, Assaraf YG.
Bram EE, et al.
Biochem Pharmacol. 2007 Jun 30;74(1):41-53. doi: 10.1016/j.bcp.2007.03.028. Epub 2007 Apr 1.
Biochem Pharmacol. 2007.
PMID: 17481587
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Structural determinants of imidazoacridinones facilitating antitumor activity are crucial for substrate recognition by ABCG2.
Bram EE, Adar Y, Mesika N, Sabisz M, Skladanowski A, Assaraf YG.
Bram EE, et al.
Mol Pharmacol. 2009 May;75(5):1149-59. doi: 10.1124/mol.109.054791. Epub 2009 Feb 27.
Mol Pharmacol. 2009.
PMID: 19251825
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