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UK-78,282, a novel piperidine compound that potently blocks the Kv1.3 voltage-gated potassium channel and inhibits human T cell activation.
Hanson DC, Nguyen A, Mather RJ, Rauer H, Koch K, Burgess LE, Rizzi JP, Donovan CB, Bruns MJ, Canniff PC, Cunningham AC, Verdries KA, Mena E, Kath JC, Gutman GA, Cahalan MD, Grissmer S, Chandy KG. Hanson DC, et al. Among authors: bruns mj. Br J Pharmacol. 1999 Apr;126(8):1707-16. doi: 10.1038/sj.bjp.0702480. Br J Pharmacol. 1999. PMID: 10372812 Free PMC article.