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Hepatic OATP and OCT uptake transporters: their role for drug-drug interactions and pharmacogenetic aspects.
Drug Metab Rev. 2010 Aug;42(3):380-401. doi: 10.3109/03602530903491683.
Drug Metab Rev. 2010.
PMID: 20100011
Review.
Phase I and II metabolism and MRP2-mediated export of bosentan in a MDCKII-OATP1B1-CYP3A4-UGT1A1-MRP2 quadruple-transfected cell line.
Fahrmayr C, König J, Auge D, Mieth M, Münch K, Segrestaa J, Pfeifer T, Treiber A, Fromm M.
Fahrmayr C, et al.
Br J Pharmacol. 2013 May;169(1):21-33. doi: 10.1111/bph.12126.
Br J Pharmacol. 2013.
PMID: 23387445
Free PMC article.
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Identification of drugs and drug metabolites as substrates of multidrug resistance protein 2 (MRP2) using triple-transfected MDCK-OATP1B1-UGT1A1-MRP2 cells.
Fahrmayr C, König J, Auge D, Mieth M, Fromm MF.
Fahrmayr C, et al.
Br J Pharmacol. 2012 Mar;165(6):1836-1847. doi: 10.1111/j.1476-5381.2011.01672.x.
Br J Pharmacol. 2012.
PMID: 21923755
Free PMC article.
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Functional and structural relevance of conserved positively charged lysine residues in organic anion transporting polypeptide 1B3.
Mandery K, Sticht H, Bujok K, Schmidt I, Fahrmayr C, Balk B, Fromm MF, Glaeser H.
Mandery K, et al. Among authors: fahrmayr c.
Mol Pharmacol. 2011 Sep;80(3):400-6. doi: 10.1124/mol.111.071282. Epub 2011 Jun 3.
Mol Pharmacol. 2011.
PMID: 21642393
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