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2007 1
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2010 2
2011 3
2012 1
2013 2
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Page 1
Structure-activity relationship studies of sulfonylpiperazine analogues as novel negative allosteric modulators of human neuronal nicotinic receptors.
Henderson BJ, Carper DJ, González-Cestari TF, Yi B, Mahasenan K, Pavlovicz RE, Dalefield ML, Coleman RS, Li C, McKay DB. Henderson BJ, et al. Among authors: gonzalez cestari tf. J Med Chem. 2011 Dec 22;54(24):8681-92. doi: 10.1021/jm201294r. Epub 2011 Nov 18. J Med Chem. 2011. PMID: 22060139 Free PMC article.
Discovery of benzamide analogs as negative allosteric modulators of human neuronal nicotinic receptors: pharmacophore modeling and structure-activity relationship studies.
Yi B, Long S, González-Cestari TF, Henderson BJ, Pavlovicz RE, Werbovetz K, Li C, McKay DB. Yi B, et al. Among authors: gonzalez cestari tf. Bioorg Med Chem. 2013 Aug 1;21(15):4730-43. doi: 10.1016/j.bmc.2013.03.082. Epub 2013 Apr 6. Bioorg Med Chem. 2013. PMID: 23757208 Free PMC article.
Negative allosteric modulators that target human alpha4beta2 neuronal nicotinic receptors.
Henderson BJ, Pavlovicz RE, Allen JD, González-Cestari TF, Orac CM, Bonnell AB, Zhu MX, Boyd RT, Li C, Bergmeier SC, McKay DB. Henderson BJ, et al. Among authors: gonzalez cestari tf. J Pharmacol Exp Ther. 2010 Sep 1;334(3):761-74. doi: 10.1124/jpet.110.168211. Epub 2010 Jun 15. J Pharmacol Exp Ther. 2010. PMID: 20551292 Free PMC article.
Analogs of methyllycaconitine as novel noncompetitive inhibitors of nicotinic receptors: pharmacological characterization, computational modeling, and pharmacophore development.
McKay DB, Chang C, González-Cestari TF, McKay SB, El-Hajj RA, Bryant DL, Zhu MX, Swaan PW, Arason KM, Pulipaka AB, Orac CM, Bergmeier SC. McKay DB, et al. Among authors: gonzalez cestari tf. Mol Pharmacol. 2007 May;71(5):1288-97. doi: 10.1124/mol.106.033233. Epub 2007 Feb 16. Mol Pharmacol. 2007. PMID: 17308033
Effect of novel negative allosteric modulators of neuronal nicotinic receptors on cells expressing native and recombinant nicotinic receptors: implications for drug discovery.
González-Cestari TF, Henderson BJ, Pavlovicz RE, McKay SB, El-Hajj RA, Pulipaka AB, Orac CM, Reed DD, Boyd RT, Zhu MX, Li C, Bergmeier SC, McKay DB. González-Cestari TF, et al. J Pharmacol Exp Ther. 2009 Feb;328(2):504-15. doi: 10.1124/jpet.108.144576. Epub 2008 Nov 4. J Pharmacol Exp Ther. 2009. PMID: 18984653 Free PMC article.