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Cyclooxygenase-1, not cyclooxygenase-2, is responsible for physiological production of prostacyclin in the cardiovascular system.
Kirkby NS, Lundberg MH, Harrington LS, Leadbeater PD, Milne GL, Potter CM, Al-Yamani M, Adeyemi O, Warner TD, Mitchell JA. Kirkby NS, et al. Among authors: harrington ls. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17597-602. doi: 10.1073/pnas.1209192109. Epub 2012 Oct 8. Proc Natl Acad Sci U S A. 2012. PMID: 23045674 Free PMC article.
P2X1 receptors and the endothelium.
Harrington LS, Mitchell JA. Harrington LS, et al. Mem Inst Oswaldo Cruz. 2005 Mar;100 Suppl 1:111-2. doi: 10.1590/s0074-02762005000900019. Epub 2005 Jun 14. Mem Inst Oswaldo Cruz. 2005. PMID: 15962108 Free article.
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