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Metabotropic glutamate receptor 1 acts as a dependence receptor creating a requirement for glutamate to sustain the viability and growth of human melanomas.
Gelb T, Pshenichkin S, Rodriguez OC, Hathaway HA, Grajkowska E, DiRaddo JO, Wroblewska B, Yasuda RP, Albanese C, Wolfe BB, Wroblewski JT. Gelb T, et al. Among authors: hathaway ha. Oncogene. 2015 May 21;34(21):2711-20. doi: 10.1038/onc.2014.231. Epub 2014 Jul 28. Oncogene. 2015. PMID: 25065592 Free PMC article.