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Year Number of Results
1980 1
1983 1
1984 1
1988 1
1990 2
1991 1
1992 2
1994 2
1996 2
1997 2
1998 2
2003 2
2005 1
2006 6
2007 2
2008 2
2009 1
2011 4
2012 4
2013 5
2014 5
2015 3
2016 7
2017 5
2018 2
2019 2
2020 4
2021 4
2022 2
2023 5
2024 3

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79 results

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Page 1
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis.
Kagan VE, Mao G, Qu F, Angeli JP, Doll S, Croix CS, Dar HH, Liu B, Tyurin VA, Ritov VB, Kapralov AA, Amoscato AA, Jiang J, Anthonymuthu T, Mohammadyani D, Yang Q, Proneth B, Klein-Seetharaman J, Watkins S, Bahar I, Greenberger J, Mallampalli RK, Stockwell BR, Tyurina YY, Conrad M, Bayır H. Kagan VE, et al. Among authors: kapralov aa. Nat Chem Biol. 2017 Jan;13(1):81-90. doi: 10.1038/nchembio.2238. Epub 2016 Nov 14. Nat Chem Biol. 2017. PMID: 27842066 Free PMC article.
Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death.
Kapralov AA, Yang Q, Dar HH, Tyurina YY, Anthonymuthu TS, Kim R, St Croix CM, Mikulska-Ruminska K, Liu B, Shrivastava IH, Tyurin VA, Ting HC, Wu YL, Gao Y, Shurin GV, Artyukhova MA, Ponomareva LA, Timashev PS, Domingues RM, Stoyanovsky DA, Greenberger JS, Mallampalli RK, Bahar I, Gabrilovich DI, Bayır H, Kagan VE. Kapralov AA, et al. Nat Chem Biol. 2020 Mar;16(3):278-290. doi: 10.1038/s41589-019-0462-8. Epub 2020 Feb 17. Nat Chem Biol. 2020. PMID: 32080625 Free PMC article.
PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.
Wenzel SE, Tyurina YY, Zhao J, St Croix CM, Dar HH, Mao G, Tyurin VA, Anthonymuthu TS, Kapralov AA, Amoscato AA, Mikulska-Ruminska K, Shrivastava IH, Kenny EM, Yang Q, Rosenbaum JC, Sparvero LJ, Emlet DR, Wen X, Minami Y, Qu F, Watkins SC, Holman TR, VanDemark AP, Kellum JA, Bahar I, Bayır H, Kagan VE. Wenzel SE, et al. Among authors: kapralov aa. Cell. 2017 Oct 19;171(3):628-641.e26. doi: 10.1016/j.cell.2017.09.044. Cell. 2017. PMID: 29053969 Free PMC article.
Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal.
Sun WY, Tyurin VA, Mikulska-Ruminska K, Shrivastava IH, Anthonymuthu TS, Zhai YJ, Pan MH, Gong HB, Lu DH, Sun J, Duan WJ, Korolev S, Abramov AY, Angelova PR, Miller I, Beharier O, Mao GW, Dar HH, Kapralov AA, Amoscato AA, Hastings TG, Greenamyre TJ, Chu CT, Sadovsky Y, Bahar I, Bayır H, Tyurina YY, He RR, Kagan VE. Sun WY, et al. Among authors: kapralov aa. Nat Chem Biol. 2021 Apr;17(4):465-476. doi: 10.1038/s41589-020-00734-x. Epub 2021 Feb 4. Nat Chem Biol. 2021. PMID: 33542532 Free PMC article.
Anomalous peroxidase activity of cytochrome c is the primary pathogenic target in Barth syndrome.
Kagan VE, Tyurina YY, Mikulska-Ruminska K, Damschroder D, Vieira Neto E, Lasorsa A, Kapralov AA, Tyurin VA, Amoscato AA, Samovich SN, Souryavong AB, Dar HH, Ramim A, Liang Z, Lazcano P, Ji J, Schmidtke MW, Kiselyov K, Korkmaz A, Vladimirov GK, Artyukhova MA, Rampratap P, Cole LK, Niyatie A, Baker EK, Peterson J, Hatch GM, Atkinson J, Vockley J, Kühn B, Wessells R, van der Wel PCA, Bahar I, Bayir H, Greenberg ML. Kagan VE, et al. Among authors: kapralov aa. Nat Metab. 2023 Dec;5(12):2184-2205. doi: 10.1038/s42255-023-00926-4. Epub 2023 Nov 23. Nat Metab. 2023. PMID: 37996701
Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediators.
Dar HH, Mikulska-Ruminska K, Tyurina YY, Luci DK, Yasgar A, Samovich SN, Kapralov AA, Souryavong AB, Tyurin VA, Amoscato AA, Epperly MW, Shurin GV, Standley M, Holman TR, St Croix CM, Watkins SC, VanDemark AP, Rana S, Zakharov AV, Simeonov A, Marugan J, Mallampalli RK, Wenzel SE, Greenberger JS, Rai G, Bayir H, Bahar I, Kagan VE. Dar HH, et al. Among authors: kapralov aa. Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2218896120. doi: 10.1073/pnas.2218896120. Epub 2023 Jun 16. Proc Natl Acad Sci U S A. 2023. PMID: 37327313 Free PMC article.
Redox phospholipidomics discovers pro-ferroptotic death signals in A375 melanoma cells in vitro and in vivo.
Tyurina YY, Kapralov AA, Tyurin VA, Shurin G, Amoscato AA, Rajasundaram D, Tian H, Bunimovich YL, Nefedova Y, Herrick WG, Parchment RE, Doroshow JH, Bayir H, Srivastava AK, Kagan VE. Tyurina YY, et al. Among authors: kapralov aa. Redox Biol. 2023 May;61:102650. doi: 10.1016/j.redox.2023.102650. Epub 2023 Feb 28. Redox Biol. 2023. PMID: 36870109 Free PMC article.
Inactivation of RIP3 kinase sensitizes to 15LOX/PEBP1-mediated ferroptotic death.
Lamade AM, Wu L, Dar HH, Mentrup HL, Shrivastava IH, Epperly MW, St Croix CM, Tyurina YY, Anthonymuthu TS, Yang Q, Kapralov AA, Huang Z, Mao G, Amoscato AA, Hier ZE, Artyukhova MA, Shurin G, Rosenbaum JC, Gough PJ, Bertin J, VanDemark AP, Watkins SC, Mollen KP, Bahar I, Greenberger JS, Kagan VE, Whalen MJ, Bayır H. Lamade AM, et al. Among authors: kapralov aa. Redox Biol. 2022 Apr;50:102232. doi: 10.1016/j.redox.2022.102232. Epub 2022 Jan 10. Redox Biol. 2022. PMID: 35101798 Free PMC article.
79 results