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Kinetic Profile of Neuropeptide-Receptor Interactions.
Nederpelt I, Bunnik J, IJzerman AP, Heitman LH. Nederpelt I, et al. Trends Neurosci. 2016 Dec;39(12):830-839. doi: 10.1016/j.tins.2016.09.008. Epub 2016 Oct 25. Trends Neurosci. 2016. PMID: 27793433 Review.
Kinetics for Drug Discovery: an industry-driven effort to target drug residence time.
Schuetz DA, de Witte WEA, Wong YC, Knasmueller B, Richter L, Kokh DB, Sadiq SK, Bosma R, Nederpelt I, Heitman LH, Segala E, Amaral M, Guo D, Andres D, Georgi V, Stoddart LA, Hill S, Cooke RM, De Graaf C, Leurs R, Frech M, Wade RC, de Lange ECM, IJzerman AP, Müller-Fahrnow A, Ecker GF. Schuetz DA, et al. Among authors: nederpelt i. Drug Discov Today. 2017 Jun;22(6):896-911. doi: 10.1016/j.drudis.2017.02.002. Epub 2017 Apr 13. Drug Discov Today. 2017. PMID: 28412474 Review.
Characterization of 12 GnRH peptide agonists - a kinetic perspective.
Nederpelt I, Georgi V, Schiele F, Nowak-Reppel K, Fernández-Montalván AE, IJzerman AP, Heitman LH. Nederpelt I, et al. Br J Pharmacol. 2016 Jan;173(1):128-41. doi: 10.1111/bph.13342. Epub 2015 Nov 4. Br J Pharmacol. 2016. PMID: 26398856 Free PMC article.
Multiple binding sites for small-molecule antagonists at the CC chemokine receptor 2.
Zweemer AJ, Nederpelt I, Vrieling H, Hafith S, Doornbos ML, de Vries H, Abt J, Gross R, Stamos D, Saunders J, Smit MJ, Ijzerman AP, Heitman LH. Zweemer AJ, et al. Among authors: nederpelt i. Mol Pharmacol. 2013 Oct;84(4):551-61. doi: 10.1124/mol.113.086850. Epub 2013 Jul 22. Mol Pharmacol. 2013. PMID: 23877010