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Page 1
Irreversible Activation and Stabilization of Soluble Guanylate Cyclase by the Protoporphyrin IX Mimetic Cinaciguat.
Mol Pharmacol. 2018 Feb;93(2):73-78. doi: 10.1124/mol.117.109918. Epub 2017 Nov 14.
Mol Pharmacol. 2018.
PMID: 29138269
Free PMC article.
Aldehyde dehydrogenase-independent bioactivation of nitroglycerin in porcine and bovine blood vessels.
Neubauer R, Wölkart G, Opelt M, Schwarzenegger C, Hofinger M, Neubauer A, Kollau A, Schmidt K, Schrammel A, Mayer B.
Neubauer R, et al. Among authors: opelt m.
Biochem Pharmacol. 2015 Feb 15;93(4):440-8. doi: 10.1016/j.bcp.2014.12.021. Epub 2015 Jan 8.
Biochem Pharmacol. 2015.
PMID: 25576686
Free PMC article.
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Intact mitochondrial Ca2+ uniport is essential for agonist-induced activation of endothelial nitric oxide synthase (eNOS).
Charoensin S, Eroglu E, Opelt M, Bischof H, Madreiter-Sokolowski CT, Kirsch A, Depaoli MR, Frank S, Schrammel A, Mayer B, Waldeck-Weiermair M, Graier WF, Malli R.
Charoensin S, et al. Among authors: opelt m.
Free Radic Biol Med. 2017 Jan;102:248-259. doi: 10.1016/j.freeradbiomed.2016.11.049. Epub 2016 Dec 5.
Free Radic Biol Med. 2017.
PMID: 27923677
Free PMC article.
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Real-time visualization of distinct nitric oxide generation of nitric oxide synthase isoforms in single cells.
Eroglu E, Hallström S, Bischof H, Opelt M, Schmidt K, Mayer B, Waldeck-Weiermair M, Graier WF, Malli R.
Eroglu E, et al. Among authors: opelt m.
Nitric Oxide. 2017 Nov 1;70:59-67. doi: 10.1016/j.niox.2017.09.001. Epub 2017 Sep 4.
Nitric Oxide. 2017.
PMID: 28882669
Free PMC article.
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Sustained Formation of Nitroglycerin-Derived Nitric Oxide by Aldehyde Dehydrogenase-2 in Vascular Smooth Muscle without Added Reductants: Implications for the Development of Nitrate Tolerance.
Opelt M, Wölkart G, Eroglu E, Waldeck-Weiermair M, Malli R, Graier WF, Kollau A, Fassett JT, Schrammel A, Mayer B, Gorren ACF.
Opelt M, et al.
Mol Pharmacol. 2018 Apr;93(4):335-343. doi: 10.1124/mol.117.110783. Epub 2018 Jan 22.
Mol Pharmacol. 2018.
PMID: 29358221
Free PMC article.
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Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017.
Todd Milne G; on behalf of the Ironwood team; Sandner P, Lincoln KA, Harrison PC, Chen H, Wang H, Clifford H, Qian HS, Wong D, Sarko C, Fryer R, Richman J, Reinhart GA, Boustany CM, Pullen SS, Andresen H, Moltzau LR, Cataliotti A, Levy FO, Lukowski R, Frankenreiter S, Friebe A, Calamaras T, Baumgartner R, McLaughlin A, Aronovitz M, Baur W, Wang GR, Kapur N, Karas R, Blanton R, Hell S, Waldman SA, Lin JE, Colon-Gonzalez F, Kim GW, Blomain ES, Merlino D, Snook A, Erdmann J, Wobst J, Kessler T, Schunkert H, Walter U, Pagel O, Walter E, Gambaryan S, Smolenski A, Jurk K, Zahedi R, Klinger JR, Benza RL, Corris PA, Langleben D, Naeije R, Simonneau G, Meier C, Colorado P, Chang MK, Busse D, Hoeper MM, Masferrer JL, Jacobson S, Liu G, Sarno R, Bernier S, Zhang P, Todd Milne G, Flores-Costa R, Currie M, Hall K, Möhrle D, Reimann K, Wolter S, Wolters M, Mergia E, Eichert N, Geisler HS, Ruth P, Friebe A, Feil R, Zimmermann U, Koesling D, Knipper M, Rüttiger L, Tanaka Y, Okamoto A, Nojiri T, Kumazoe M, Tokudome T, Miura K, Hino J, Hosoda H, Miyazato M, Kangawa K, Kapil V, Ahluwalia A, Paolocci N, Eaton P, Campbell JC, Henning P, Franz E, Sankaran B, Herberg FW, Kim C, Wittwer M, Luo Q, Kaila V…
See abstract for full author list ➔
Todd Milne G, et al. Among authors: opelt m.
BMC Pharmacol Toxicol. 2017 Oct 10;18(Suppl 1):64. doi: 10.1186/s40360-017-0170-5.
BMC Pharmacol Toxicol. 2017.
PMID: 29035170
Free PMC article.
No abstract available.
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Formation of Nitric Oxide by Aldehyde Dehydrogenase-2 Is Necessary and Sufficient for Vascular Bioactivation of Nitroglycerin.
Opelt M, Eroglu E, Waldeck-Weiermair M, Russwurm M, Koesling D, Malli R, Graier WF, Fassett JT, Schrammel A, Mayer B.
Opelt M, et al.
J Biol Chem. 2016 Nov 11;291(46):24076-24084. doi: 10.1074/jbc.M116.752071. Epub 2016 Sep 27.
J Biol Chem. 2016.
PMID: 27679490
Free PMC article.
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