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1990 2
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A site-directed mutagenesis study on Escherichia coli inorganic pyrophosphatase. Glutamic acid-98 and lysine-104 are important for structural integrity, whereas aspartic acids-97 and -102 are essential for catalytic activity.
Lahti R, Pohjanoksa K, Pitkäranta T, Heikinheimo P, Salminen T, Meyer P, Heinonen J. Lahti R, et al. Among authors: pohjanoksa k. Biochemistry. 1990 Jun 19;29(24):5761-6. doi: 10.1021/bi00476a017. Biochemistry. 1990. PMID: 1974462
Amphetamine decreases α2C-adrenoceptor binding of [11C]ORM-13070: a PET study in the primate brain.
Finnema SJ, Hughes ZA, Haaparanta-Solin M, Stepanov V, Nakao R, Varnäs K, Varrone A, Arponen E, Marjamäki P, Pohjanoksa K, Vuorilehto L, Babalola PA, Solin O, Grimwood S, Sallinen J, Farde L, Scheinin M, Halldin C. Finnema SJ, et al. Among authors: pohjanoksa k. Int J Neuropsychopharmacol. 2014 Dec 13;18(3):pyu081. doi: 10.1093/ijnp/pyu081. Int J Neuropsychopharmacol. 2014. PMID: 25522417 Free PMC article.
Octopamine receptors from the barnacle balanus improvisus are activated by the alpha2-adrenoceptor agonist medetomidine.
Lind U, Alm Rosenblad M, Hasselberg Frank L, Falkbring S, Brive L, Laurila JM, Pohjanoksa K, Vuorenpää A, Kukkonen JP, Gunnarsson L, Scheinin M, Mårtensson Lindblad LG, Blomberg A. Lind U, et al. Among authors: pohjanoksa k. Mol Pharmacol. 2010 Aug;78(2):237-48. doi: 10.1124/mol.110.063594. Epub 2010 May 20. Mol Pharmacol. 2010. PMID: 20488921
Might the observed α(2A)-adrenoreceptor agonism or antagonism of allyphenyline analogues be ascribed to different molecular conformations?
Diamanti E, Del Bello F, Carbonara G, Carrieri A, Fracchiolla G, Giannella M, Mammoli V, Piergentili A, Pohjanoksa K, Quaglia W, Scheinin M, Pigini M. Diamanti E, et al. Among authors: pohjanoksa k. Bioorg Med Chem. 2012 Mar 15;20(6):2082-90. doi: 10.1016/j.bmc.2012.01.035. Epub 2012 Jan 31. Bioorg Med Chem. 2012. PMID: 22341244
12 results