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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 1
1973 1
1976 1
1977 1
1983 1
1986 3
1987 3
1988 7
1989 1
1990 6
1991 1
1992 3
1994 1
1999 1
2000 1
2001 1
2002 2
2004 5
2005 6
2006 12
2007 7
2008 10
2009 9
2010 8
2011 10
2012 16
2013 20
2014 10
2015 13
2016 16
2017 9
2018 20
2019 15
2020 10
2021 21
2022 17
2023 15
2024 4

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263 results

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Page 1
RLY-4008, the First Highly Selective FGFR2 Inhibitor with Activity across FGFR2 Alterations and Resistance Mutations.
Subbiah V, Sahai V, Maglic D, Bruderek K, Touré BB, Zhao S, Valverde R, O'Hearn PJ, Moustakas DT, Schönherr H, Gerami-Moayed N, Taylor AM, Hudson BM, Houde DJ, Pal D, Foster L, Gunaydin H, Ayaz P, Sharon DA, Goyal L, Schram AM, Kamath S, Sherwin CA, Schmidt-Kittler O, Jen KY, Ricard F, Wolf BB, Shaw DE, Bergstrom DA, Watters J, Casaletto JB. Subbiah V, et al. Among authors: shaw de. Cancer Discov. 2023 Sep 6;13(9):2012-2031. doi: 10.1158/2159-8290.CD-23-0475. Cancer Discov. 2023. PMID: 37270847 Free PMC article.
Mechanism of NMDA receptor channel block by MK-801 and memantine.
Song X, Jensen MØ, Jogini V, Stein RA, Lee CH, Mchaourab HS, Shaw DE, Gouaux E. Song X, et al. Among authors: shaw de. Nature. 2018 Apr;556(7702):515-519. doi: 10.1038/s41586-018-0039-9. Epub 2018 Apr 18. Nature. 2018. PMID: 29670280 Free PMC article.
Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia.
Varkaris A, Pazolli E, Gunaydin H, Wang Q, Pierce L, Boezio AA, Bulku A, DiPietro L, Fridrich C, Frost A, Giordanetto F, Hamilton EP, Harris K, Holliday M, Hunter TL, Iskandar A, Ji Y, Larivée A, LaRochelle JR, Lescarbeau A, Llambi F, Lormil B, Mader MM, Mar BG, Martin I, McLean TH, Michelsen K, Pechersky Y, Puente-Poushnejad E, Raynor K, Rogala D, Samadani R, Schram AM, Shortsleeves K, Swaminathan S, Tajmir S, Tan G, Tang Y, Valverde R, Wehrenberg B, Wilbur J, Williams BR, Zeng H, Zhang H, Walters WP, Wolf BB, Shaw DE, Bergstrom DA, Watters J, Fraser JS, Fortin PD, Kipp DR. Varkaris A, et al. Among authors: shaw de. Cancer Discov. 2024 Feb 8;14(2):240-257. doi: 10.1158/2159-8290.CD-23-0944. Cancer Discov. 2024. PMID: 37916956 Free PMC article.
Stratification of asthma by lipidomic profiling of induced sputum supernatant.
Brandsma J, Schofield JPR, Yang X, Strazzeri F, Barber C, Goss VM, Koster G, Bakke PS, Caruso M, Chanez P, Dahlén SE, Fowler SJ, Horváth I, Krug N, Montuschi P, Sanak M, Sandström T, Shaw DE, Chung KF, Singer F, Fleming LJ, Adcock IM, Pandis I, Bansal AT, Corfield J, Sousa AR, Sterk PJ, Sánchez-García RJ, Skipp PJ, Postle AD, Djukanović R; U-BIOPRED Study Group. Brandsma J, et al. Among authors: shaw de. J Allergy Clin Immunol. 2023 Jul;152(1):117-125. doi: 10.1016/j.jaci.2023.02.032. Epub 2023 Mar 12. J Allergy Clin Immunol. 2023. PMID: 36918039 Free article.
The role of inflammation in anxiety and depression in the European U-BIOPRED asthma cohorts.
Hou R, Ye G, Cheng X, Shaw DE, Bakke PS, Caruso M, Dahlen B, Dahlen SE, Fowler SJ, Horváth I, Howarth P, Krug N, Montuschi P, Sanak M, Sandström T, Auffray C, De Meulder B, Sousa AR, Adcock IM, Fan Chung K, Sterk PJ, Skipp PJ, Schofield J, Djukanović R; U-BIOPRED Study Group. Hou R, et al. Among authors: shaw de. Brain Behav Immun. 2023 Jul;111:249-258. doi: 10.1016/j.bbi.2023.04.011. Epub 2023 May 3. Brain Behav Immun. 2023. PMID: 37146653 Free article.
A multi-omics approach to delineate sputum microbiome-associated asthma inflammatory phenotypes.
Abdel-Aziz MI, Vijverberg SJH, Neerincx AH, Brinkman P, Wagener AH, Riley JH, Sousa AR, Bates S, Wagers SS, De Meulder B, Auffray C, Wheelock ÅM, Bansal AT, Caruso M, Chanez P, Uddin M, Corfield J, Horvath I, Krug N, Musial J, Sun K, Shaw DE, Sandström T, Montuschi P, Fowler SJ, Lutter R, Djukanovic R, Howarth P, Skipp P, Sanak M, Adcock IM, Chung KF, Sterk PJ, Kraneveld AD, Maitland-van der Zee AH; U-BIOPRED Study Group. Abdel-Aziz MI, et al. Among authors: shaw de. Eur Respir J. 2022 Jan 13;59(1):2102603. doi: 10.1183/13993003.02603-2021. Print 2022 Jan. Eur Respir J. 2022. PMID: 34824056 Free article. No abstract available.
Desensitization dynamics of the AMPA receptor.
Aittoniemi J, Jensen MØ, Pan AC, Shaw DE. Aittoniemi J, et al. Among authors: shaw de. Structure. 2023 Jun 1;31(6):724-734.e3. doi: 10.1016/j.str.2023.03.013. Epub 2023 Apr 13. Structure. 2023. PMID: 37059095 Free article.
Molecular determinants of drug-receptor binding kinetics.
Pan AC, Borhani DW, Dror RO, Shaw DE. Pan AC, et al. Among authors: shaw de. Drug Discov Today. 2013 Jul;18(13-14):667-73. doi: 10.1016/j.drudis.2013.02.007. Epub 2013 Feb 27. Drug Discov Today. 2013. PMID: 23454741 Review.
263 results