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2007 1
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2009 5
2010 3
2011 5
2012 7
2013 5
2014 3
2015 3
2016 1
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2019 5
2020 4
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66 results

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Page 1
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors.
Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA, Abbracchio MP, Abraham G, Agoulnik A, Alexander W, Al-Hosaini K, Bäck M, Baker JG, Barnes NM, Bathgate R, Beaulieu JM, Beck-Sickinger AG, Behrens M, Bernstein KE, Bettler B, Birdsall NJM, Blaho V, Boulay F, Bousquet C, Bräuner-Osborne H, Burnstock G, Caló G, Castaño JP, Catt KJ, Ceruti S, Chazot P, Chiang N, Chini B, Chun J, Cianciulli A, Civelli O, Clapp LH, Couture R, Cox HM, Csaba Z, Dahlgren C, Dent G, Douglas SD, Dournaud P, Eguchi S, Escher E, Filardo EJ, Fong T, Fumagalli M, Gainetdinov RR, Garelja ML, de Gasparo M, Gerard C, Gershengorn M, Gobeil F, Goodfriend TL, Goudet C, Grätz L, Gregory KJ, Gundlach AL, Hamann J, Hanson J, Hauger RL, Hay DL, Heinemann A, Herr D, Hollenberg MD, Holliday ND, Horiuchi M, Hoyer D, Hunyady L, Husain A, IJzerman AP, Inagami T, Jacobson KA, Jensen RT, Jockers R, Jonnalagadda D, Karnik S, Kaupmann K, Kemp J, Kennedy C, Kihara Y, Kitazawa T, Kozielewicz P, Kreienkamp HJ, Kukkonen JP, Langenhan T, Larhammar D, Leach K, Lecca D, Lee JD, Leeman SE, Leprince J, Li XX, Lolait SJ, Lupp A, Macrae R, Maguire J, Malfaci… See abstract for full author list ➔ Alexander SPH, et al. Among authors: valant c. Br J Pharmacol. 2023 Oct;180 Suppl 2:S23-S144. doi: 10.1111/bph.16177. Br J Pharmacol. 2023. PMID: 38123151 Free article.
Structural basis of efficacy-driven ligand selectivity at GPCRs.
Powers AS, Pham V, Burger WAC, Thompson G, Laloudakis Y, Barnes NW, Sexton PM, Paul SM, Christopoulos A, Thal DM, Felder CC, Valant C, Dror RO. Powers AS, et al. Among authors: valant c. Nat Chem Biol. 2023 Jul;19(7):805-814. doi: 10.1038/s41589-022-01247-5. Epub 2023 Feb 13. Nat Chem Biol. 2023. PMID: 36782010 Free PMC article.
Xanomeline displays concomitant orthosteric and allosteric binding modes at the M4 mAChR.
Burger WAC, Pham V, Vuckovic Z, Powers AS, Mobbs JI, Laloudakis Y, Glukhova A, Wootten D, Tobin AB, Sexton PM, Paul SM, Felder CC, Danev R, Dror RO, Christopoulos A, Valant C, Thal DM. Burger WAC, et al. Among authors: valant c. Nat Commun. 2023 Sep 6;14(1):5440. doi: 10.1038/s41467-023-41199-5. Nat Commun. 2023. PMID: 37673901 Free PMC article.
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors.
Alexander SP, Christopoulos A, Davenport AP, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Abbracchio MP, Alexander W, Al-Hosaini K, Bäck M, Barnes NM, Bathgate R, Beaulieu JM, Bernstein KE, Bettler B, Birdsall NJM, Blaho V, Boulay F, Bousquet C, Bräuner-Osborne H, Burnstock G, Caló G, Castaño JP, Catt KJ, Ceruti S, Chazot P, Chiang N, Chini B, Chun J, Cianciulli A, Civelli O, Clapp LH, Couture R, Csaba Z, Dahlgren C, Dent G, Singh KD, Douglas SD, Dournaud P, Eguchi S, Escher E, Filardo EJ, Fong T, Fumagalli M, Gainetdinov RR, Gasparo M, Gerard C, Gershengorn M, Gobeil F, Goodfriend TL, Goudet C, Gregory KJ, Gundlach AL, Hamann J, Hanson J, Hauger RL, Hay DL, Heinemann A, Hollenberg MD, Holliday ND, Horiuchi M, Hoyer D, Hunyady L, Husain A, IJzerman AP, Inagami T, Jacobson KA, Jensen RT, Jockers R, Jonnalagadda D, Karnik S, Kaupmann K, Kemp J, Kennedy C, Kihara Y, Kitazawa T, Kozielewicz P, Kreienkamp HJ, Kukkonen JP, Langenhan T, Leach K, Lecca D, Lee JD, Leeman SE, Leprince J, Li XX, Williams TL, Lolait SJ, Lupp A, Macrae R, Maguire J, Mazella J, McArdle CA, Melmed S, Michel MC, Miller LJ, Mitolo V, Mouillac B, Mül… See abstract for full author list ➔ Alexander SP, et al. Among authors: valant c. Br J Pharmacol. 2021 Oct;178 Suppl 1:S27-S156. doi: 10.1111/bph.15538. Br J Pharmacol. 2021. PMID: 34529832 Free article.
Endogenous allosteric modulators of G protein-coupled receptors.
van der Westhuizen ET, Valant C, Sexton PM, Christopoulos A. van der Westhuizen ET, et al. Among authors: valant c. J Pharmacol Exp Ther. 2015 May;353(2):246-60. doi: 10.1124/jpet.114.221606. Epub 2015 Feb 3. J Pharmacol Exp Ther. 2015. PMID: 25650376 Review.
Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics.
Vuckovic Z, Wang J, Pham V, Mobbs JI, Belousoff MJ, Bhattarai A, Burger WAC, Thompson G, Yeasmin M, Nawaratne V, Leach K, van der Westhuizen ET, Khajehali E, Liang YL, Glukhova A, Wootten D, Lindsley CW, Tobin A, Sexton P, Danev R, Valant C, Miao Y, Christopoulos A, Thal DM. Vuckovic Z, et al. Among authors: valant c. Elife. 2023 May 30;12:e83477. doi: 10.7554/eLife.83477. Elife. 2023. PMID: 37248726 Free PMC article.
Fine Tuning Muscarinic Acetylcholine Receptor Signaling Through Allostery and Bias.
van der Westhuizen ET, Choy KHC, Valant C, McKenzie-Nickson S, Bradley SJ, Tobin AB, Sexton PM, Christopoulos A. van der Westhuizen ET, et al. Among authors: valant c. Front Pharmacol. 2021 Jan 29;11:606656. doi: 10.3389/fphar.2020.606656. eCollection 2020. Front Pharmacol. 2021. PMID: 33584282 Free PMC article. Review.
66 results