Marijuana and related drugs (cannabinoids) have been proposed as treatments for a
widening spectrum of medical disorders.R(+)-[2,3-dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo[…

The endogenous cannabinoids (endocannabinoids) anandamide and 2-arachidonylglycerol
increased cell viability in cerebral cortical neuron cultures subjected to 8 h of hypoxia and …

In addition to its better-known hemopoietic action, erythropoietin (Epo) has neurotrophic
properties and neuroprotective effects in some models of hypoxic-ischemic injury. To define …

Although most cells in the embryonic mouse cortex express the serine-threonine kinase Akt-1,
a small population of progenitors expresses Akt-1 protein at a higher level. To determine …

Vascular endothelial growth factor (VEGF) couples hypoxia to angiogenesis in ischemic tissues,
including brain. Since hypoxia induces VEGF mRNA in astroglial cultures, we examined …

Pharmacological and molecular biological studies provide evidence for subtypes of sodium‐dependent
high‐affinity glutamate (Glu) transport in the mammalian CNS. At least some of …

Before the discovery of the metabotropic glutamate receptors (mGIuRs), the glutamate
analogue L-2-amino-4-phosphonobutanoic acid (L-AP4) was identified as a potent presynaptic …

T‐cell restricted intracellular antigen‐related protein (TIAR) is an RNA recognition motif‐type
RNA‐binding protein that has been implicated in the apoptotic death of T‐lymphocytes and …

… Previously, we isolated ES cells from a mouse model of SMA and found that motor
neurons produced from these ES cells die soon after differentiation (ADS-A., HDN and LLR, …

… Sinor … Sinor, and recommend that it be accepted toward the partial Mfillment of the
requirements for the degree of Doctor of Philosophy. … Sinor University of Pittsburgh, 2004 …