User profiles for A Wellstein
 | Anton WellsteinGeorgetown University Verified email at georgetown.edu Cited by 15845 |
[PDF][PDF] Fibroblast growth factors, their receptors and signaling.
…, SW McLeskey, A Wellstein - Endocrine-related …, 2000 - erc.bioscientifica.com
Fibroblast growth factors (FGFs) are small polypeptide growth factors, all of whom share in
common certain structural characteristics, and most of whom bind heparin avidly. Many FGFs …
common certain structural characteristics, and most of whom bind heparin avidly. Many FGFs …
[HTML][HTML] Circulating biomarkers to monitor cancer progression and treatment
Tumor heterogeneity is a major challenge and the root cause of resistance to treatment. Still,
the standard diagnostic approach relies on the analysis of a single tumor sample from a …
the standard diagnostic approach relies on the analysis of a single tumor sample from a …
The role and regulation of the nuclear receptor co-activator AIB1 in breast cancer
T Lahusen, RT Henke, BL Kagan, A Wellstein… - Breast cancer research …, 2009 - Springer
AIB1 (amplified in breast cancer 1), also called SRC-3 and NCoA-3, is a member of the p160
nuclear receptor co-activator family and is considered an important oncogene in breast …
nuclear receptor co-activator family and is considered an important oncogene in breast …
Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma
…, F Wang, B Kallakury, J Toretsky, A Wellstein… - Science …, 2014 - science.org
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with poor survival rates
and frequently carries oncogenic KRAS mutation. However, KRAS has thus far not been a …
and frequently carries oncogenic KRAS mutation. However, KRAS has thus far not been a …
[HTML][HTML] Pleiotrophin stimulates fibroblasts and endothelial and epithelial cells and is expressed in human cancer.
…, N Hartmann, DT Chow, AT Riegel, A Wellstein - Journal of Biological …, 1992 - Elsevier
Previously we reported the purification of the heparin-binding growth factor pleiotrophin (PTN)
from supernatants of the human breast cancer cell line MDA-MB-231. To investigate …
from supernatants of the human breast cancer cell line MDA-MB-231. To investigate …
Human trophoblast and choriocarcinoma expression of the growth factor pleiotrophin attributable to germ-line insertion of an endogenous retrovirus
…, F Czubayko, AT Riegel, A Wellstein - Proceedings of the …, 1996 - National Acad Sciences
Retroviral elements are found in abundance throughout the human genome but only rarely
have alterations of endogenous genes by retroviral insertions been described. Herein we …
have alterations of endogenous genes by retroviral insertions been described. Herein we …
[HTML][HTML] Pleiotrophin signaling through anaplastic lymphoma kinase is rate-limiting for glioblastoma growth
…, A Aigner, GE Stoica, K McDonnell, A Wellstein - Journal of Biological …, 2002 - ASBMB
Glioblastoma multiforme is the most common highly aggressive human brain cancer, and
receptor tyrosine kinases have been implicated in the progression of this malignancy. We have …
receptor tyrosine kinases have been implicated in the progression of this malignancy. We have …
Immunolocalization of an FGF-binding protein reveals a widespread expression pattern during different stages of mouse embryo development
A Aigner, PE Ray, F Czubayko, A Wellstein - Histochemistry and cell …, 2002 - Springer
Fibroblast growth factors (FGFs) play important roles during fetal and embryonic development.
FGF-2 (basic FGF, bFGF) is widely expressed in the embryo and has been linked to tissue …
FGF-2 (basic FGF, bFGF) is widely expressed in the embryo and has been linked to tissue …
[HTML][HTML] Identification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophin
…, D Wen, A Karavanov, AT Riegel, A Wellstein - Journal of Biological …, 2001 - ASBMB
Pleiotrophin (PTN) is a secreted growth factor that induces neurite outgrowth and is mitogenic
for fibroblasts, epithelial, and endothelial cells. During tumor growth PTN can serve as an …
for fibroblasts, epithelial, and endothelial cells. During tumor growth PTN can serve as an …
[HTML][HTML] Enhancement of fibroblast growth factor (FGF) activity by an FGF-binding protein
…, K McDonnell, A Karavanov, A Wellstein - Journal of Biological …, 2001 - ASBMB
Fibroblast growth factor-binding protein (FGF-BP) 1 is a secreted protein that can bind
fibroblast growth factors (FGFs) 1 and 2. These FGFs are typically stored on heparan sulfate …
fibroblast growth factors (FGFs) 1 and 2. These FGFs are typically stored on heparan sulfate …