Chronic infection with hepatitis C virus (HCV) affects 170 million people worldwide and is
the leading cause of cirrhosis in North America 1 . Although the recommended treatment for …

New evidence and consensus has led to further revision of the McDonald Criteria for diagnosis
of multiple sclerosis. The use of imaging for demonstration of dissemination of central …

… The original McDonald Criteria as they applied to PPMS were based on the work of Thompson
and colleagues,34 which provided criteria derived for rigorous research purposes rather …

The 2010 McDonald criteria for the diagnosis of multiple sclerosis are widely used in research
and clinical practice. Scientific advances in the past 7 years suggest that they might no …

Accurate clinical course descriptions (phenotypes) of multiple sclerosis (MS) are important
for communication, prognostication, design and recruitment of clinical trials, and treatment …

Evidence concerning anatomical connectivities in the human brain is sparse and based largely
on limited post-mortem observations. Diffusion tensor imaging has previously been used …

… Thompson is chair of the MSIF International Medical and Scientific Board (no remuneration),
chair of the Eisai-… Professor Alan Thompson: drafting and critical revision of the manuscript. …

Recovery of motor function after stroke may occur over weeks or months and is often attributed
to cerebral reorganization. We have investigated the longitudinal relationship between …

A major component in the regulatory network controlling fruit ripening is likely to be the gene
at the tomato Colorless non-ripening (Cnr) locus 1 , 2 . The Cnr mutation results in colorless …

Clinically isolated syndromes (CIS), such as optic neuritis, brainstem or spinal cord syndromes
are frequently the first clinical presentations of multiple sclerosis. However, not all CIS …