The effect of 5-fluorouracil on the synthesis of nuclear RNA in L1210 cells in vitro

RI GLAZER, ANNL PEALE - Molecular Pharmacology, 1979 - ASPET
The effect of 5-fluorouracil on nuclear RNA synthesis and its incorporation into nuclear RNA
were studied in L1210 cells in vitro. Inhibition of the incorporation of [ 3 H]uridine into total …

Potentiation by 2′-Deoxycoformycin of the Inhibitory Effect by 3′-Deoxyadenosine (Cordycepin) on Nuclear RNA Synthesis in L1210 Cells in Vitro

RI Glazer, TJ Lott, AL Peale - Cancer Research, 1978 - AACR
The effect of the adenosine deaminase inhibitor, 2′-deoxycoformycin, on the inhibitory effect
of cordycepin on nuclear RNA synthesis was examined in L1210 cells in vitro. The median …

Measurement of S-adenosyl-L-methionine levels by SP Sephadex chromatography

RI Glazer, AL Peale - Analytical Biochemistry, 1978 - Elsevier
Cation-exchange chromatography with sulfopropyl Sephadex was used to measure the levels
of S-[methyl- 3 H]adenosyl-l-methionine synthesized by L1210 cells in vitro. Separation of …

[PDF][PDF] The effect of 5-azacytidine and dihydro-5-azacytidine on nuclear ribosomal RNA and poly (A) RNA synthesis in L1210 cells in vitro

RI Glazer, AL Peale, JA Beisler, MM Abbasi - Molecular pharmacology, 1980 - Citeseer
GLAZER, RI, AL PEALE, JA BEISLER AND MM ABBASI. The effect of 5-azacytidine and
dihydro-5-azacytidine on nuclear nbosomal RNA and poly (A) RNA synthesis in L1210 cells in …

Cordycepin and xylosyladenine: inhibitors of methylation of nuclear RNA

RI Glazer, AL Peale - Biochemical and Biophysical Research …, 1978 - Elsevier
Cordycepin and xylosyladenine inhibited methylation of nuclear RNA to a greater extent
than RNA synthesis in L1210 cells in vitro . Inhibition of base methylation, 2′-0-methylation …

Comparison between the inhibitory activities of sangivamycin and thiosangivamycin on nuclear ribonucleic acid synthesis in L1210 cells in vitro

RI Glazer, AL Peale - Biochemical Pharmacology, 1980 - Elsevier
The molecular effects of the pyrrolopyrimidine analogs, sangivamycin and thiosangivamycin,
on RNA and DNA synthesis were examined in L1210 cells in vitro. Pretreatment of cells for …

Potentiation by 2'-deoxycoformycin of the inhibitory effect of xylosyladenine on nuclear RNA synthesis in L1210 cells in vitro

AL Peale, RI Glazer - Biochemical Pharmacology, 1978 - Elsevier
The effect of the adenosine deaminase inhibitor, 2'-deoxycoformycin (dCF), on the inhibitory
effect of 9-β-d-xylofuranosyladenine (XA) on nuclear RNA synthesis was examined in …

Evidence that xylosyladenine affects methylation by inhibition of S-adenosyl-L-methionine synthesis

RI Glazer, AL Peale - Cancer Letters, 1979 - Elsevier
The adenosine analogs, 9-β-D-xylofuranosyladenine (XA) and 3′-deoxyadenosine (cordycepin)
were tested for their ability to interfer with S-adenosyl-L-methionine (SAM) formation in …

Tolerance of long-term methotrexate infusions by mice

…, RL Dedrick, DM Young, AL Peale - Biochemical Pharmacology, 1976 - Elsevier
Mice were chronically exposed to between 1 × 10 −8 and 5 × 10 −9 M plasma methotrexate (MTX)
for 2 months. No signs of toxicity were manifested except minor facial hair loss. At the …

Sustained release formulations of rhVEGF165 produce a durable response in a murine model of peripheral angiogenesis

…, LK Rangell, R Eckert, J Zavala-Solorio, F Peale… - European journal of …, 2011 - Elsevier
Local delivery of therapeutic angiogenic agents that stimulate blood vessel formation represents
a promising strategy for the treatment of peripheral vascular disease (PVD). At present, …