On the reversibility of binding of cardiotonic steroids to a partially purified (Na+ K)-activated adenosinetriphosphatase from beef brain

A Yoda, LE Hokin - Biochemical and biophysical research communications, 1970 - Elsevier
Incubation of a partially purified preparation of NaK ATPase from beef brain with various
cardiotonic steroids under conditions of maximum binding of the steroid to the enzyme, followed …

Evidence that a phosphorylated intermediate in a brain transport adenosine triphosphatase is an acyl phosphate.

…, PS Sastry, PR Galsworthy, A Yoda - Proceedings of the …, 1965 - National Acad Sciences
It is now fairly well established that an adenosine triphosphatase (ATPase) which is present
in a variety of membrane preparations is closely related to coupled Na+ and K+ transport. 1-…

Structure-Activity Relationships of Cardiotonic Steroids for the Inhibition of Sodium-and Potassium-Dependent Adenosine Triphosphatase: II. Association Rate …

A YODA, S YODA, AM SARRIF - Molecular pharmacology, 1973 - ASPET
The association rate constants (k a ) of cardiac glycoside-(Na + + K + )-ATPase (EC 3.6.1.3 )
complexes at 25 in presence of magnesium and phosphate and of sodium, magnesium, and …

Interaction between ouabain and the phosphorylated intermediate of Na, K-ATPase.

A Yoda, S Yoda - Molecular pharmacology, 1982 - ASPET
After phosphorylation of electric eel Na,K-ATPase by Na+, Mg2+, and ATP was terminated
by removing the unbound Mg2+, the phosphoenzyme was able to bind ouabain upon the …

Inhibition by diisopropylfluorophosphate of a kidney transport adenosine triphosphatase by phosphorylation of a serine residue

LE Hokin, A Yoda - Proceedings of the National Academy of …, 1964 - National Acad Sciences
Higherconcentrations of CaCl2completely preven ed the DFP inhibition. There was some
inhibition of the transport to-S4 1O_ lo-4 lo-n 0-l2 10. ATPase activity by Ca++ in the absence …

Reconstitution of (Na++ K+)-ATPase proteoliposomes having the same turnover rate as the membranous enzyme

A Yoda, AW Clark, S Yoda - Biochimica et Biophysica Acta (BBA) …, 1984 - Elsevier
Membranous (Na + + K + )-ATPase from the electric eel was solubilized with 3-((3-cholamidopropyl)-dimethylammonio)-1-propanesulfonate
(Chaps). 50 to 70% of the solubilized …

Association and dissociation rate constants of the complexes between various cardiac aglycones and sodium-and potassium-dependent adenosine triphosphatase …

A YODA, S YODA - Molecular Pharmacology, 1977 - ASPET
Association and dissociation rates of cardiac aglycone-(Na + + K + -ATPase complexes formed
in the presence of magnesium and inorganic phosphate were examined by assay of the …

[PDF][PDF] Formation of ADP-sensitive phosphorylated intermediate in the electric eel Na, K-ATPase preparation.

A Yoda, S Yoda - Molecular pharmacology, 1982 - Citeseer
The ADP-sensitive and K-sensitive phosphorylated forms of Na, K-ATPase(E1P and E2P,
respectively) are believed to be the main phosphorylated intermediates of Na, K-ATPase. In …

A new simple preparation method for NaK-ATPase-rich membrane fragments

A Yoda, S Yoda - Analytical Biochemistry, 1981 - Elsevier
A method for the isolation of highly active membrane bound NaK-ATPase without detergents
in quantity from the electric organ of the electric eel (Electrophorus electricus) is described. …

Structure-Activity Relationships of Cardiotonic Steroids for the Inhibition of Sodium-and Potassium-Dependent Adenosine Triphosphatase: III. Dissociation Rate …

A YODA, S YODA - Molecular pharmacology, 1974 - ASPET
The dissociation rate constants (k d ) of cardiac monoglycoside—(Na + + K + )-ATPase
complexes formed in the Na + -Mg 2+ -ATP system (type I complex) were determined by …