User profiles for Adrian D. Sproul
Adrian SproulAmerican Medical Response Verified email at gmr.net Cited by 158 |
Agonist-induced conformational changes in the extracellular domain of α7 nicotinic acetylcholine receptors
LK Lyford, AD Sproul, D Eddins, JT McLaughlin… - Molecular …, 2003 - ASPET
The molecular mechanisms that couple agonist binding to the gating of Cys-loop ionotropic
receptors are not well understood. The crystal structure of the acetylcholine (ACh) binding …
receptors are not well understood. The crystal structure of the acetylcholine (ACh) binding …
Role of the outer β-sheet in divalent cation modulation of α7 nicotinic receptors
JT McLaughlin, J Fu, AD Sproul, RL Rosenberg - Molecular pharmacology, 2006 - ASPET
α-7 Nicotinic acetylcholine receptors (AChRs) exhibit a positive modulation by divalent cations
similar to that observed in other AChRs. In the chick α7 AChR, this modulation involves a …
similar to that observed in other AChRs. In the chick α7 AChR, this modulation involves a …
Glutamate 172, essential for modulation of L247T α7 ACh receptors by Ca2+, lines the extracellular vestibule
D Eddins, AD Sproul, LK Lyford… - … of Physiology-Cell …, 2002 - journals.physiology.org
Neuronal α 7 nicotinic ACh receptors (nAChRs) are permeable to and modulated by Ca 2+ ,
Ba 2+ , and Sr 2+ . These permeant divalent cations interact with slowly desensitizing L 247 …
Ba 2+ , and Sr 2+ . These permeant divalent cations interact with slowly desensitizing L 247 …
Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer
Aberrant promoter hypermethylation is frequently observed in cancer. The potential for this
mechanism to contribute to tumor development depends on whether the genes affected are …
mechanism to contribute to tumor development depends on whether the genes affected are …
[BOOK][B] Structures and Properties of Some Iron Triad Complexes: Iron (iii) Halide and Nickel (ii) Aquo Halide Complexes; Nickel (ii) and Nickel (iv) Pyridine Dioxime …
GD Sproul - 1971 - search.proquest.com
The number and arrangement of halide ligands coordinated to a transition metal in a complex
anion is often surprisingly dependent on the nature of cationic ions present. For example …
anion is often surprisingly dependent on the nature of cationic ions present. For example …
N-methyl-d-aspartate receptor subunit NR3a expression and function in principal cells of the collecting duct
A Sproul, SL Steele, TL Thai, SP Yu… - American Journal …, 2011 - journals.physiology.org
N-methyl-d-aspartate receptors (NMDARs) are Ca 2+ -permeable, ligand-gated, nonselective
cation channels that function as neuronal synaptic receptors but which are also expressed …
cation channels that function as neuronal synaptic receptors but which are also expressed …
Transplantation of embryonic stem cells improves nerve repair and functional recovery after severe sciatic nerve axotomy in rats
… (D): Quantification of sciatic nerve diameter at the proximal stump site 1 and 3 months after
… The authors thank Adrian D. Sproul for his assistance in editing the manuscript. LC and JJ …
… The authors thank Adrian D. Sproul for his assistance in editing the manuscript. LC and JJ …
Critical Roles of the Na+/K+-ATPase in Apoptosis and CNS Diseases
A Sproul, X Zhou, SP Yu - Brain Hypoxia and Ischemia: with Special …, 2009 - Springer
The Na + /K + -ATPase is a transmembrane protein that serves as the primary electrogenic
ion transporter in the plasma membrane of all mammalian cells. In addition to this critical …
ion transporter in the plasma membrane of all mammalian cells. In addition to this critical …
[HTML][HTML] Observations of the total solar eclipse of September 10, 1923, by the Sproul Observatory
JA Miller, RW Marriott - Sproul Observatory publications; no. 7 …, 1925 - adsabs.harvard.edu
… Sproul negatives, there is a series of six additional fainter arches similar in shape and above
… on the arches as measured in inches on the Sproul and Douglas plates respectively. The …
… on the arches as measured in inches on the Sproul and Douglas plates respectively. The …
Comparison of allogeneic vs autologous bone marrow–derived mesenchymal stem cells delivered by transendocardial injection in patients with ischemic …
…, PV Johnston, JA Brinker, E Breton, J Davis-Sproul… - Jama, 2012 - jamanetwork.com
Context Mesenchymal stem cells (MSCs) are under evaluation as a therapy for ischemic
cardiomyopathy (ICM). Both autologous and allogeneic MSC therapies are possible; however, …
cardiomyopathy (ICM). Both autologous and allogeneic MSC therapies are possible; however, …