User profiles for Amey S. Dhopeshwarkar
 | amey dhopeshwarkarAssistant Scientist Verified email at indiana.edu Cited by 819 |
Slowly signaling G protein–biased CB2 cannabinoid receptor agonist LY2828360 suppresses neuropathic pain with sustained efficacy and attenuates morphine …
The CB 2 cannabinoid agonist LY2828360 lacked both toxicity and efficacy in a clinical trial
for osteoarthritis. Whether LY2828360 suppresses neuropathic pain has not been reported, …
for osteoarthritis. Whether LY2828360 suppresses neuropathic pain has not been reported, …
Cannabinoid CB2 agonist AM1710 differentially suppresses distinct pathological pain states and attenuates morphine tolerance and withdrawal
AL Li, X Lin, AS Dhopeshwarkar, AC Thomaz… - Molecular …, 2019 - ASPET
AM1710 (3-(1,1-dimethyl-heptyl)-1-hydroxy-9-methoxy-benzo(c) chromen-6-one), a
cannabilactone cannabinoid receptor 2 (CB2) agonist, suppresses chemotherapy-induced …
cannabilactone cannabinoid receptor 2 (CB2) agonist, suppresses chemotherapy-induced …
The G protein-coupled cannabinoid-1 (CB1) receptor of mammalian brain: inhibition by phthalate esters in vitro
KM Bisset, AS Dhopeshwarkar, C Liao… - Neurochemistry …, 2011 - Elsevier
This research examines the in vitro interaction of phthalate diesters and monoesters with the
G protein-coupled cannabinoid 1 (CB 1 ) receptor, a presynaptic complex involved in the …
G protein-coupled cannabinoid 1 (CB 1 ) receptor, a presynaptic complex involved in the …
The actions of benzophenanthridine alkaloids, piperonyl butoxide and (S)-methoprene at the G-protein coupled cannabinoid CB1 receptor in vitro
AS Dhopeshwarkar, S Jain, C Liao, SK Ghose… - European journal of …, 2011 - Elsevier
This investigation focused primarily on the interaction of two benzophenanthridine alkaloids
(chelerythrine and sanguinarine), piperonyl butoxide and (S)-methoprene with G-protein-…
(chelerythrine and sanguinarine), piperonyl butoxide and (S)-methoprene with G-protein-…
Actions of benzophenanthridine alkaloids and various synthetic compounds on the cannabinoid-1 (CB1) receptor pathway of mouse brain with particular reference to …
AS Dhopeshwarkar - 2012 - summit.sfu.ca
Benzophenanthridine alkaloids chelerythrine and sanguinarine inhibited the binding of
3HCP55940 and 3HSR141716A to mouse brain membranes IC50s approx. 1-2 µM. Piperonyl …
3HCP55940 and 3HSR141716A to mouse brain membranes IC50s approx. 1-2 µM. Piperonyl …
Benzophenanthridine alkaloid, piperonyl butoxide and (S)-methoprene action at the cannabinoid-1 receptor (CB1-receptor) pathway of mouse brain: Interference with …
AS Dhopeshwarkar, RA Nicholson - European Journal of Pharmacology, 2014 - Elsevier
… After verifying the IC 50 s of sanguinarine, chelerythrine, piperonyl butoxide and (S)-methoprene
that we … AS Dhopeshwarkar conducted all experiments as part of his Ph.D. research. …
that we … AS Dhopeshwarkar conducted all experiments as part of his Ph.D. research. …
CB2 cannabinoid receptors as a therapeutic target—what does the future hold?
A Dhopeshwarkar, K Mackie - Molecular pharmacology, 2014 - ASPET
The past decades have seen an exponential rise in our understanding of the endocannabinoid
system, comprising CB 1 and CB 2 cannabinoid receptors, endogenous cannabinoids (…
system, comprising CB 1 and CB 2 cannabinoid receptors, endogenous cannabinoids (…
Functional selectivity of CB2 cannabinoid receptor ligands at a canonical and noncanonical pathway
A Dhopeshwarkar, K Mackie - Journal of pharmacology and experimental …, 2016 - ASPET
The CB2 cannabinoid receptor (CB 2 ) remains a tantalizing, but unrealized therapeutic target.
CB 2 receptor ligands belong to varied structural classes and display extreme functional …
CB 2 receptor ligands belong to varied structural classes and display extreme functional …
Two Janus cannabinoids that are both CB2 agonists and CB1 antagonists
A Dhopeshwarkar, N Murataeva, A Makriyannis… - … of Pharmacology and …, 2017 - ASPET
The cannabinoid signaling system includes two G protein–coupled receptors, CB 1 and CB
2 . These receptors are widely distributed throughout the body and have each been …
2 . These receptors are widely distributed throughout the body and have each been …
Where's my entourage? The curious case of 2-oleoylglycerol, 2-linolenoylglycerol, and 2-palmitoylglycerol
N Murataeva, A Dhopeshwarkar, D Yin… - Pharmacological …, 2016 - Elsevier
2-Arachidonoylglycerol (2-AG) is the most abundant endogenous cannabinoid in the brain
and an agonist at two cannabinoid receptors (CB 1 and CB 2 ). The synthesis, degradation …
and an agonist at two cannabinoid receptors (CB 1 and CB 2 ). The synthesis, degradation …