A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase.

EY Krynetski, JD Schuetz, AJ Galpin… - Proceedings of the …, 1995 - National Acad Sciences
Thiopurine S-methyltransferase (TPMT; S-adenosyl-L-methionine:thiopurine S-methyltransferase,
EC 2.1.1.67) activity exhibits genetic polymorphism, with approximately 0.33% of …

Differences in folylpolyglutamate synthetase and dihydrofolate reductase expression in human B-lineage versus T-lineage leukemic lymphoblasts: mechanisms for …

AJ Galpin, JD Schuetz, E Masson, Y Yanishevski… - Molecular …, 1997 - ASPET
Cellular accumulation of methotrexate polyglutamates (MTXPGs) is recognized as an
important determinant of the cytotoxicity and selectivity of methotrexate in acute lymphoblastic …

Therapeutic drug monitoring in cancer management

AJ Galpin, WE Evans - Clinical chemistry, 1993 - academic.oup.com
Several anticancer drugs display characteristics that make them suitable candidates for
therapeutic drug monitoring (TDM), including substantial pharmacokinetic variability and a …

'The dots just don't join up': Understanding the support needs of families of children on the autism spectrum

J Galpin, P Barratt, E Ashcroft, S Greathead… - …, 2018 - journals.sagepub.com
Much research has documented the elevated levels of stress experienced by families of
autistic children. Yet remarkably little research has examined the types of support that these …

[HTML][HTML] The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation

…, A Korshunov, T Hielscher, PA Northcott, JD Galpin… - Cell, 2013 - cell.com
Metabolic adaptation is essential for cell survival during nutrient deprivation. We report that
eukaryotic elongation factor 2 kinase (eEF2K), which is activated by AMP-kinase (AMPK), …

Bench press and pushup repetitions to failure with equated load

…, A Lin, JW Coburn, AJ Galpin… - … Journal of Sports …, 2017 - journals.sagepub.com
The bench press and pushup are commonly used for training upper body muscular strength
and endurance. Although they are often used interchangeably, differences between the two …

[BOOK][B] The anxiety workbook for supporting teens who learn differently: a Framework and Activities to build structural, sensory and social certainty

C Ward, J Galpin - 2021 - books.google.com
… The idea for an actual book came from an out of the blue conversation with Amy Lankester-Owen
at JKP when Clare was looking for new therapy ideas for young people with more than …

[BOOK][B] Rural clubs in Wisconsin

CJ Galpin - 1916 - books.google.com
Good farming depends on good neighboring. Living on good terms with folks is a part of
modern farming as truly as knowing how to farm. A higher level of efficiency is reached in the …

[HTML][HTML] Effects of starting stance on base running sprint speed in softball players

…, CM Watkins, SR Barillas, AJ Galpin… - … Journal of Exercise …, 2018 - ncbi.nlm.nih.gov
Speed is a crucial aspect in softball, and can be the difference between winning and losing.
Base stealing is a method used to produce runs. There has been debate over which starting …

[BOOK][B] The Work of the Experiment Station and Agricultural Extension Service for 1916: The Director's Annual Report

…, CJ Galpin, GC Humphrey, JG Milward, J Johnson… - 1916 - books.google.com
… The country church an economic and social force by CJ Galpin … Chemistry AS
Alexander, Veterinary Science; In charge of Stallion Enrollment FA AUST, Horticulture BA …