Mutations in BRIP1 confer high risk of ovarian cancer

…, MD García-Prats, C Mayordomo, A Panadero… - Nature …, 2011 - nature.com
Ovarian cancer causes more deaths than any other gynecologic malignancy in developed
countries. Sixteen million sequence variants, identified through whole-genome sequencing of …

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

…, MD García-Prats, E Sanambrosio, A Panadero… - Nature …, 2011 - nature.com
To identify new risk variants for cutaneous basal cell carcinoma, we performed a genome-wide
association study of 16 million SNPs identified through whole-genome sequencing of …

Discovery of common variants associated with low TSH levels and thyroid cancer risk

…, TS Plantinga, M Den Heijer, E Aguillo, A Panadero… - Nature …, 2012 - nature.com
To search for sequence variants conferring risk of nonmedullary thyroid cancer, we focused
our analysis on 22 SNPs with a P < 5 × 10 −8 in a genome-wide association study on levels …

European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene

…, S Guarrera, C Sacerdote, A Panadero… - Human molecular …, 2011 - academic.oup.com
Three genome-wide association studies in Europe and the USA have reported eight urinary
bladder cancer (UBC) susceptibility loci. Using extended case and control series and 1000 …

[HTML][HTML] A genome-wide association study yields five novel thyroid cancer risk loci

…, MD Ringel, E Aguillo, A Panadero… - Nature …, 2017 - nature.com
The great majority of thyroid cancers are of the non-medullary type. Here we report findings
from a genome-wide association study of non-medullary thyroid cancer, including in total …

[HTML][HTML] Ancestry-Shift Refinement Mapping of the C6orf97-ESR1 Breast Cancer Susceptibility Locus

…, JM Ramon-Cajal, A De Juan, A Panadero… - PLoS …, 2010 - journals.plos.org
We used an approach that we term ancestry-shift refinement mapping to investigate an
association, originally discovered in a GWAS of a Chinese population, between rs2046210[T] …

[HTML][HTML] A common variant at 8q24. 21 is associated with renal cell cancer

…, OT Magnusson, H Helgason, A Panadero… - Nature …, 2013 - nature.com
Renal cell carcinoma (RCC) represents between 80 and 90% of kidney cancers. Previous
genome-wide association studies of RCC have identified five variants conferring risk of the …

Genome-wide association study yields variants at 20p12. 2 that associate with urinary bladder cancer

…, TE Galesloot, A De Juan, A Panadero… - Human molecular …, 2014 - academic.oup.com
Genome-wide association studies (GWAS) of urinary bladder cancer (UBC) have yielded
common variants at 12 loci that associate with risk of the disease. We report here the results of …

Genome-wide significant association between a sequence variant at 15q15. 2 and lung cancer risk

…, D Isla, L Murillo, MD García-Prats, A Panadero… - Cancer research, 2011 - AACR
Genome-wide association studies (GWAS) have identified 3 genomic regions, at 15q24–25.1,
5p15.33, and 6p21.33, which associate with the risk of lung cancer. Large meta-analyses …

Insertion of an SVA-E retrotransposon into the CASP8 gene is associated with protection against prostate cancer

…, RG Cremers, A Panadero… - Human molecular …, 2016 - academic.oup.com
Transcriptional and splicing anomalies have been observed in intron 8 of the CASP8 gene (encoding
procaspase-8) in association with cutaneous basal-cell carcinoma (BCC) and …