Mitochondria are dynamic organelles that exchange contents and undergo remodelling
during cyclic fusion and fission. Genetic mutations in MFN2 (the gene encoding mitofusin 2) …

Endogenous neurosteroids have rapid actions on ion channels, particularly GABA A receptors,
which are potentiated by nanomolar concentrations of 3α-hydroxypregnane neurosteroids…

To address the question of the relative contributions of glial and neuronal glutamate transport
in the vertebrate CNS, we studied the distribution of forebrain glutamate transporters in rat …

The ability to fuel neurons via glycogenolysis is believed to be an important function of glia.
Indeed, the slow, rather than immediate, depression of synaptic transmission in hippocampal …

Recent evidence implicates the endogenous excitotoxin, glutamate (Glu), in several neurologic
disorders, including seizure‐related brain damage. Ketamine, phencyclidine, and MK‐…

Glutamate appears to play a major role in several degenerative retinal disorders. However,
exogenous glutamate is only weakly toxic to the retina when glutamate transporters on …

To determine whether ketone bodies sustain neuronal function as energy substrates, we
examined the effects of beta-hydroxybutyrate (betaHB) on synaptic transmission and …

We characterized morphological effects of the endogenous excitotoxin, glutamate in ex vivo
retinal segments prepared from 30-day-old rats. Initial changes induced by glutamate …

RAT hippocampal slices were used to evaluate the effects of glucose deprivation and the
ability of lactate or pyruvate to preserve histological integrity and synaptic function. Dark cell …

Although inhibitors of glutamate transport prolong synaptic currents at many glutamate
synapses, the cause of the current prolongation is unclear. Transport inhibitors may prolong …