User profiles for Anthony Gavalas

Anthony Gavalas

Verified email at tu-dresden.de
Cited by 2458

Novel effectors of directed and Ngn3-mediated differentiation of mouse embryonic stem cells into endocrine pancreas progenitors

…, I Rakatzi, V Episkopou, M Gouti, A Gavalas - Stem …, 2008 - academic.oup.com
The delineation of regulatory networks involved in early endocrine pancreas specification will
play a crucial role in directing the differentiation of embryonic stem cells toward the mature …

[HTML][HTML] Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling

…, K Yoshioka, Y Takuwa, A Dahl, D Pan, A Gavalas - PLoS …, 2017 - journals.plos.org
During development, progenitor expansion, lineage allocation, and implementation of
differentiation programs need to be tightly coordinated so that different cell types are generated in …

[HTML][HTML] ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools

…, L Arnes, L Sussel, S Singh, V Vasiliou, A Gavalas - Developmental …, 2013 - Elsevier
Aldehyde dehydrogenase (ALDH) genes are increasingly associated with stem/progenitor
cell status but their role in the maintenance of pluripotency remains uncertain. In a screen …

Genetic interactions between Hoxa1 and Hoxb1 reveal new roles in regulation of early hindbrain patterning

M Studer, A Gavalas, H Marshall… - …, 1998 - journals.biologists.com
In the developing vertebrate hindbrain Hoxa1 and Hoxb1 play important roles in patterning
segmental units (rhombomeres). In this study, genetic analysis of double mutants …

Hoxa1 and Hoxb1 synergize in patterning the hindbrain, cranial nerves and second pharyngeal arch

A Gavalas, M Studer, A Lumsden, FM Rijli… - …, 1998 - journals.biologists.com
The analysis of Hoxa1 and Hoxb1 null mutants suggested that these genes are involved in
distinct aspects of hindbrain segmentation and specification. Here we investigate the …

Role of Hoxa-2 in axon pathfinding and rostral hindbrain patterning

A Gavalas, M Davenne, A Lumsden… - …, 1997 - journals.biologists.com
Segmentation plays an important role in neuronal diversification and organisation in the
developing hindbrain. For instance, cranial nerve branchiomotor nuclei are organised …

Retinoid signalling and hindbrain patterning

A Gavalas, R Krumlauf - Current opinion in genetics & development, 2000 - Elsevier
Retinoid signalling has been implicated in regulating a wide variety of processes in
vertebrate development. Recent advances from analyses on the synthesis, degradation and …

Neuronal defects in the hindbrain of Hoxa1, Hoxb1 and Hoxb2 mutants reflect regulatory interactions among these Hox genes

A Gavalas, C Ruhrberg, J Livet, CE Henderson… - 2003 - journals.biologists.com
Hox genes are instrumental in assigning segmental identity in the developing hindbrain.
Auto-, cross- and para-regulatory interactions help establish and maintain their expression. To …

Synergy between Hoxa1 and Hoxb1: the relationship between arch patterning and the generation of cranial neural crest

A Gavalas, P Trainor, L Ariza-McNaughton, R Krumlauf - 2001 - journals.biologists.com
Hoxa1 and Hoxb1 have overlapping synergistic roles in patterning the hindbrain and cranial
neural crest cells. The combination of an ectoderm-specific regulatory mutation in the …

Transcriptional repression coordinates the temporal switch from motor to serotonergic neurogenesis

…, AL Ferri, C Milton, F Prin, P Pla, W Lin, A Gavalas… - Nature …, 2007 - nature.com
In many regions of the developing CNS, distinct cell types are born at different times. The
means by which discrete and stereotyped temporal switches in cellular identities are acquired …