MYC (also known as c-MYC) overexpression or hyperactivation is one of the most common
drivers of human cancer. Despite intensive study, the MYC oncogene remains recalcitrant to …

The diffuse-type gastric cancer (DGC) is a subtype of gastric cancer with the worst prognosis
and few treatment options. Here we present a dataset from 84 DGC patients, composed of a …

Neuropathological aggregates of the intrinsically disordered microtubule-associated protein
Tau are hallmarks of Alzheimer’s disease, with decades of research devoted to studying the …

Astrocytes play essential roles in brain function by supporting synaptic connectivity and
associated circuits. How these roles are regulated by transcription factors is unknown. Moreover, …

Stress granules (SGs) are large macromolecular aggregates that contain translation initiation
complexes and mRNAs. Stress granule formation coincides with translational repression, …

Murine studies showed that disruption of circadian clock rhythmicity could lead to cancer and
metabolic syndrome. Time-restricted feeding can reset the disrupted clock rhythm, protect …

Emerging evidence suggests that cryptic translation within long noncoding RNAs (lncRNAs)
may produce novel proteins with important developmental/physiological functions. However…

Metabolic syndrome is characterized by central obesity, insulin resistance, elevated blood
pressure, and dyslipidemia. Metabolic syndrome is a significant risk factor for several common …

The identification of major histocompatibility complex (MHC)‐binding peptides in mass
spectrometry (MS)‐based immunopeptideomics relies largely on database search engines …

In quantitative mass spectrometry, the method by which peptides are grouped into proteins
can have dramatic effects on downstream analyses. Here we describe gpGrouper, an …