Quantification of biofilm structures by the novel computer program comstat

A Heydorn, AT Nielsen, M Hentzer… - …, 2000 - microbiologyresearch.org
The structural organization of four microbial communities was analysed by a novel computer
program, COMSTAT, which comprises ten features for quantifying three-dimensional biofilm …

Biofilm formation by Pseudomonas aeruginosa wild type, flagella and type IV pili mutants

M Klausen, A Heydorn, P Ragas… - Molecular …, 2003 - Wiley Online Library
Biofilm formation by Gfp‐tagged Pseudomonas aeruginosa PAO1 wild type, flagella and type
IV pili mutants in flow chambers irrigated with citrate minimal medium was characterized by …

Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound

…, K Riedel, TB Rasmussen, A Heydorn… - …, 2002 - microbiologyresearch.org
Novel molecular tools have been constructed which allow for in situ detection of N-acyl
homoserine lactone (AHL)-mediated quorum sensing in Pseudomonas aeruginosa biofilms. The …

Alginate Overproduction Affects Pseudomonas aeruginosa Biofilm Structure and Function

M Hentzer, GM Teitzel, GJ Balzer, A Heydorn… - Journal of …, 2001 - Am Soc Microbiol
During the course of chronic cystic fibrosis (CF) infections,Pseudomonas aeruginosa undergoes
a conversion to a mucoid phenotype, which is characterized by overproduction of the …

The cep quorum-sensing system of Burkholderia cepacia H111 controls biofilm formation and swarming motility

B Huber, K Riedel, M Hentzer, A Heydorn… - …, 2001 - microbiologyresearch.org
Burkholderia cepacia and Pseudomonas aeruginosa often co-exist as mixed biofilms in the
lungs of patients suffering from cystic fibrosis (CF). Here, the isolation of random mini-Tn5 …

[HTML][HTML] The exopolysaccharide matrix modulates the interaction between 3D architecture and virulence of a mixed-species oral biofilm

…, B Lu, CM Delahunty, JR Yates III, A Heydorn… - PLoS …, 2012 - journals.plos.org
Virulent biofilms are responsible for a range of infections, including oral diseases. All biofilms
harbor a microbial-derived extracellular-matrix. The exopolysaccharides (EPS) formed on …

Stratified Growth in Pseudomonas aeruginosa Biofilms

…, A Bugnicourt, MJ Franklin, A Heydorn… - Applied and …, 2004 - Am Soc Microbiol
In this study, stratified patterns of protein synthesis and growth were demonstrated in
Pseudomonas aeruginosa biofilms. Spatial patterns of protein synthetic activity inside biofilms were …

gfp-Based N-Acyl Homoserine-Lactone Sensor Systems for Detection of Bacterial Communication

JB Andersen, A Heydorn, M Hentzer… - Applied and …, 2001 - Am Soc Microbiol
In order to perform single-cell analysis and online studies ofN-acyl homoserine lactone (AHL)-mediated
communication among bacteria, components of the Vibrio fischeri quorum …

Statistical Analysis of Pseudomonas aeruginosa Biofilm Development: Impact of Mutations in Genes Involved in Twitching Motility, Cell-to-Cell Signaling, and …

A Heydorn, B Ersbøll, J Kato, M Hentzer… - Applied and …, 2002 - Am Soc Microbiol
Four strains of Pseudomonas aeruginosa (wild type, ΔpilHIJK mutant, lasI mutant, and rpoS
mutant) were genetically tagged with the green fluorescent protein, and the development of …

Experimental reproducibility in flow-chamber biofilms

A Heydorn, BK Ersbøll, M Hentzer… - …, 2000 - microbiologyresearch.org
The structural organization of microbial communities is influenced by many factors, eg
nutrient composition, shear stress and temperature. This paper presents a general method for …