[PDF][PDF] Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

…, TP Neufeld, I Nishino, RA Nixon, T Noda, B Nürnberg… - Autophagy, 2008 - Taylor & Francis
Research in autophagy continues to accelerate, 1 and as a result many new scientists are
entering the field. Accordingly, it is important to establish a standard set of criteria for …

Receptors and G proteins as primary components of transmembrane signal transduction: Part 1. G-protein-coupled receptors: structure and function

T Gudermann, B Nürnberg, G Schultz - Journal of molecular medicine, 1995 - Springer
Specialized cells in a living organism communicate with each other through extracellular
molecules such as hormones, neurotransmitters, and growth factors. An immediate selection of …

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

…, B Vanhaesebroeck, R Dhand, B Nürnberg… - Science, 1995 - science.org
… (B) Sequence comparison of part of the kinase domain of p10y, human p110cx (12), human
… through which pllOt and p110 bind p85ct and p85,B (13). However, the sequence of p1iO~…

[HTML][HTML] Diabetic lung disease: fact or fiction?

S Kolahian, V Leiss, B Nürnberg - Reviews in Endocrine and Metabolic …, 2019 - Springer
… Insulin increases the deposition of extracellular matrix (ECM) in the lung and promotes
epithelial-mesenchymal transition (EMT) and fibrosis via the PI3K/protein kinase B β-catenin …

Roles of Gβγ in membrane recruitment and activation of p110γ/p101 phosphoinositide 3-kinase γ

…, K Spicher, G Schultz, B Nürnberg - The Journal of cell …, 2003 - rupress.org
… Because changes in morphology are not a very reliable measure of PI3K activity, we
examined phosphorylation of endogenous protein kinase B (PKB or Akt) as an established PI3K-…

Bivalent role of the phosphatidylinositol‐3‐kinase (PI3K) during influenza virus infection and host cell defence

C Ehrhardt, H Marjuki, T Wolff, B Nürnberg… - Cellular …, 2006 - Wiley Online Library
B. MDCK cells were infected with influenza viruses FPV, WSN-HK, PR8 (moi = 3) and other
RNA viruses (Sendai, VSV, moi = 3) for 6 hC MDCK cells were infected with influenza virus …

Assessment of optical coherence tomography imaging in the diagnosis of non-melanoma skin cancer and benign lesions versus normal skin: observer-blinded …

M Mogensen, TM Joergensen, BM Nürnberg… - Dermatologic …, 2009 - journals.lww.com
BACKGROUND Optical coherence tomography (OCT) is an optical imaging technique that
may be useful in diagnosis of non-melanoma skin cancer (NMSC). OBJECTIVES To describe …

[HTML][HTML] Roles of non-catalytic subunits in Gβγ-induced activation of class I phosphoinositide 3-kinase isoforms β and γ

U Maier, A Babich, B Nurnberg - Journal of Biological Chemistry, 1999 - ASBMB
… into class I A p85- or class I B p101-associated heterodimers. Until recently this grouping …
be sensitive to tyrosine kinases, the only class I B member p110γ is activated by G-proteins. …

PI3K promotes voltage-dependent calcium channel trafficking to the plasma membrane

…, AJ Butcher, G Halet, A Davies, B Nürnberg… - Nature …, 2004 - nature.com
… (b) Quantification of the relative amounts of total cell Ca v 2.2 α 1 co-expressed in control (open
bars) and PI3Kγ-CAAX plus myr-Akt/PKB-transfected cells (closed bars). (JPG 19 kb) …

[HTML][HTML] Gβγ stimulates phosphoinositide 3-kinase-γ by direct interaction with two domains of the catalytic p110 subunit

…, T Exner, U Maier, R Wetzker, B Nurnberg - Journal of Biological …, 1998 - ASBMB
… In contrast, the only known class I B member p110γ does not bind to p85 adaptors, but …
The Sepharose-bound GST fusion proteins could be stored at −20 C in buffer B containing 50% …