Hydrogen exchange kinetics and internal motions in proteins and nucleic acids

CK Woodward, BD Hilton - Annual Review of biophysics and …, 1979 - annualreviews.org
The peptide NH protons of unstructured polypeptides exchange readily with aqueous
solvent protons. Proton exchange rates of native proteins are retarded by many orders of …

DNA adducts from carcinogenic and noncarcinogenic enantiomers of benzo [a] pyrenedihydrodiol epoxide

SC Cheng, BD Hilton, JM Roman… - Chemical research in …, 1989 - ACS Publications
The characterization of eight benzo [o] pyrene-deoxyribonucleoside adducts derived from
reaction of the onti-dihydrodiol epoxide and deoxyguanylic and deoxyadenylic acids is …

1H- and 13C-nmr Assignments for Taxol, 7-epi-Taxol, and Cephalomannine

GN Chmurny, BD Hilton, S Brobst, SA Look… - Journal of natural …, 1992 - ACS Publications
The 1H-and 13C-nmr spectra of taxol [1], 7-epi-taxol [2], and cephalomannine [3] were
assigned usingmodem ID and 2D nmr methods. Preliminary conformational information was …

Mechanism of the triphenylphosphine and diethyl azodicarboxylate induced dehydration reactions (Mitsunobu reaction). The central role of pentavalent phosphorus …

E Grochowski, BD Hilton, RJ Kupper… - Journal of the …, 1982 - ACS Publications
'H mult6 31P mult assignment 167.9 s S# 3, or a. 157.9 dd (22.1 Hz)»! or# 3, 134.3 dd (10.9
Hz) 2 or 3 133.5 dd (2.5 Hz) 4 128.5 dd (13.5 Hz) 3 or 2 121.4 sd (103.5 Hz) 1 63.2 ts a2 or …

Investigation of the experimental limits of small-sample heteronuclear 2D NMR

BD Hilton, GE Martin - Journal of natural products, 2010 - ACS Publications
Practical experimental performance limits for an ensemble of heteronuclear 2D NMR experiments
using a state-of-the-art 600 MHz 1.7 mm Bruker TCI Micro CryoProbe are reported. In …

[PDF][PDF] Hydrogen isotope exchange kinetics of single protons in bovine pancreatic trypsin inhibitor

CK Woodward, BD Hilton - Biophysical journal, 1980 - cell.com
The exchange kinetics of the slowest exchanging BPTI beta-sheet protons are complex
compared to model peptides; the activation energy, E alpha, and the pH dependence are …

Axial hydrophobic fence in highly-stable Ni (II) complex of des-angiotensinogen N-terminal peptide

W Bal, GN Chmurny, BD Hilton… - Journal of the …, 1996 - ACS Publications
Angiotensinogen is a 66 kDa globular protein circulating in human blood with a concentration
of ca. 1 μg mL-1 (15 nM). 1 The kidney protease renin cleaves the N-terminal decapeptide …

Structure of fredericamycin A, an antitumor antibiotic of a novel skeletal type; spectroscopic and mass spectral characterization

R MIOSRA, RC Pandey, BD Hilton… - The Journal of …, 1987 - jstage.jst.go.jp
IR, UV-visible spectroscopy, circular dichroism, xll and 13CNMRstudies, high resolution
electron impact, field desorption, andfast atombombardmentmassspectral studies are reported …

[PDF][PDF] Lower temperature tolerance of snook, Centropomus undecimalis

…, AJ Sonski, PL Shafland, BD Hilton - Gulf of Mexico …, 1990 - aquila.usm.edu
METHODS Eighteen subadult snook were collected in coastal waters at South Padre Island
and Port Isabel, Texas in September 1983, and were transported to Heart of the Hills …

Chemical characterization of DNA adducts derived from the configurationally isomeric benzo [c] phenanthrene-3, 4-diol 1, 2-epoxides

…, HJC Yeh, LK Pannell, BD Hilton… - Journal of the …, 1987 - ACS Publications
The chemical structures of 16 principal adducts formed from the deoxyadenosine and
deoxyguanosine residues of DNA upon reaction invitro with the fourconfigurationally isomeric 3, 4-…