Effects of moderate alcohol consumption on the central nervous system

…, H Kalant, GF Koob, TK Li, B Tabakoff - Alcoholism: Clinical …, 1998 - Wiley Online Library
The concept of moderate consumption of ethanol (beverage alcohol) has evolved over time
from considering this level of intake to be nonintoxicating and noninjurious, to encompassing …

N‐Methyl‐D‐Aspartate Receptors and Ethanol: Inhibition of Calcium Flux and Cyclic GMP Production

…, CS Rabe, F Moses, B Tabakoff - Journal of …, 1989 - Wiley Online Library
Measurements of calcium uptake and cyclic GMP production by cerebellar granule cells
grown in primary culture demonstrated that ethanol preferentially inhibited N‐methyl‐D‐…

The multiMiR R package and database: integration of microRNA–target interactions along with their disease and drug associations

Y Ru, KJ Kechris, B Tabakoff, P Hoffman… - Nucleic acids …, 2014 - academic.oup.com
microRNAs (miRNAs) regulate expression by promoting degradation or repressing translation
of target transcripts. miRNA target sites have been catalogued in databases based on …

Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis

…, JK Belknap, B Tabakoff… - Proceedings of the …, 2006 - National Acad Sciences
Much evidence from studies in humans and animals supports the hypothesis that alcohol
addiction is a complex disease with both hereditary and environmental influences. Molecular …

Ethanol withdrawal seizures and the NMDA receptor complex

…, P Valverius, M Hudspith, B Tabakoff - European journal of …, 1990 - Elsevier
Prior biochemical and electrophysiological studies have shown that low doses of ethanol
inhibited calcium influx through the N-methyl-D-aspartate (NMDA) receptor/ionophore. The …

CDT, GGT, and AST as markers of alcohol use: the WHO/ISBRA collaborative project

…, JB Saunders, A Helander, B Tabakoff… - Alcoholism: Clinical …, 2002 - Wiley Online Library
Background: Estimates of the performance of carbohydrate deficient transferrin (CDT) and
gamma glutamyltransferase (GGT) as markers of alcohol consumption have varied widely. …

Alcohol‐induced neurodegeneration: when, where and why?

…, R Pentney, LD Snell, B Tabakoff… - Alcoholism: Clinical …, 2004 - Wiley Online Library
This manuscript reviews the proceedings of a symposium organized by Drs. Antonio Noronha
and Fulton Crews presented at the 2003 Research Society on Alcoholism meeting. The …

Addictions biology: haplotype-based analysis for 130 candidate genes on a single array

…, J Mann, B Riley, A Roy, B Tabakoff… - Alcohol & …, 2008 - academic.oup.com
Aims: To develop a panel of markers able to extract full haplotype information for candidate
genes in alcoholism, other addictions and disorders of mood and anxiety. Methods: A total of …

[HTML][HTML] Animal models in alcohol research

B Tabakoff, PL Hoffman - Alcohol Research & Health, 2000 - ncbi.nlm.nih.gov
Animal models are important tools in the study of alcohol use, abuse, and dependence
because they allow researchers to use methods that cannot be used with human subjects. …

The neurobiology of alcohol consumption and alcoholism: an integrative history

B Tabakoff, PL Hoffman - Pharmacology Biochemistry and Behavior, 2013 - Elsevier
Studies of the neurobiological predisposition to consume alcohol (ethanol) and to transition
to uncontrolled drinking behavior (alcoholism), as well as studies of the effects of alcohol on …